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- Table of Contents
Facts about Mitochondrial fission factor.
May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles. .
Human | |
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Gene Name: | MFF |
Uniprot: | Q9GZY8 |
Entrez: | 56947 |
Belongs to: |
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Tango11 family |
mitochondrial fission factor
Mass (kDA):
38.465 kDA
Human | |
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Location: | 2q36.3 |
Sequence: | 2; NC_000002.12 (227325233..227357836) |
Highly expressed in heart, kidney, liver, brain, muscle, and stomach.
Mitochondrion outer membrane; Single-pass type IV membrane protein. Peroxisome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.
PMID: 18353969 by Gandre-Babbe S., et al. The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells.
PMID: 23921378 by Palmer C.S., et al. MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission.