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- Table of Contents
Facts about Mesoderm posterior protein 2.
Regulates also the FGF signaling pathway. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand.
Mouse | |
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Gene Name: | Mesp2 |
Uniprot: | O08574 |
Entrez: | 17293 |
Belongs to: |
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No superfamily |
bHLHc6; class C basic helix-loop-helix protein 6; mesoderm posterior 2 homolog (mouse); mesoderm posterior protein 2; SCDO2
Mass (kDA):
39.789 kDA
Mouse | |
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Location: | 7 D2|7 45.18 cM |
Sequence: | 7; |
PMID: 9242490 by Saga Y., et al. Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation.
PMID: 10330372 by del Barco Barrantes I., et al. Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse.