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- Table of Contents
Facts about Protein MEMO1.
The MEMO1-RHOA-DIAPH1 signaling pathway plays an significant role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 into the cell membrane, via the regulation of GSK3B activity.
Human | |
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Gene Name: | MEMO1 |
Uniprot: | Q9Y316 |
Entrez: | 7795 |
Belongs to: |
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MEMO1 family |
C21orf19-like protein; C2orf4DKFZp434I0135; CGI-27; FLJ25031; HCV NS5A-transactivated protein 7; Hepatitis C virus NS5A-transactivated protein 7; mediator of cell motility 1; Mediator of ErbB2-driven cell motility 1; memo-1; MEMOchromosome 2 open reading frame 4; NS5ATP7; protein MEMO1
Mass (kDA):
33.733 kDA
Human | |
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Location: | 1p36.1-p35 |
Sequence: | 1; |
PMID: 11707072 by Reymond A., et al. From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map.
PMID: 15156151 by Marone R., et al. Memo mediates ErbB2-driven cell motility.