Megf10 Antibodies

AND Megf10 ELISA kits, Megf10 Proteins

Many biological assays use antibodies to detect Megf10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Megf10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Megf10 antibodies...

We validate the specificity of these antibodies to Megf10 by testing them on tissues known to express Megf10 positively and negatively. Browse below to find the Megf10 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Megf10 Infographic by Boster Bio

All Megf10 Products

Product

Figures

Specificity

Applications

Price

Anti-MEGF10 Antibody

Human, Mouse, Rat

$405
Cat # A06799
100ul

MEGF10 (NM_032446) Human Over-expression Lysate

Human

$960
Cat # LS084466
100 µg

Megf10 Overview

Facts about Multiple epidermal growth factor-like domains protein 10.

Multiple epidermal growth factor-like domains protein 10 (Megf10)

Membrane receptor involved in phagocytosis by macrophages and astrocytes of apoptotic cells. Receptor for C1q, an eat-me sign, that binds phosphatidylserine expressed on the surface of apoptotic cells (PubMed:27170117).

Cooperates with ABCA1 within the process of engulfment (By similarity). Promotes the formation of large vacuoles and might be responsible for the uptake of amyloid-beta peptides (PubMed:20828568).

Gene Information

Mouse
Gene Name:	Megf10
Uniprot:	Q6DIB5
Entrez:	70417

Family

Belongs to:

MEGF family

Alternative Names

Multiple epidermal growth factor-like domains protein 10

Molecular Weight

Mass (kDA):
122.972 kDA

Genomic Context


Mouse

Location:	18\|18 D3
Sequence:	18;

Tissue Specificity

Expressed in cerebellum (at protein level). Expressed in kidney, stellate cells of the cerebellum and macrophage cell lines.

PTMs

Disulfide bond
Glycoprotein

Phosphoprotein
Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Megf10

References

PMID: 17205124 by Hamon Y., et al. Cooperation between engulfment receptors: the case of ABCA1 and MEGF10.

PMID: 17643423 by Suzuki E., et al. MEGF10 is a mammalian ortholog of CED-1 that interacts with clathrin assembly protein complex 2 medium chain and induces large vacuole formation.