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MyoD family inhibitor Antibodies

AND MDFI ELISA kits, MyoD family inhibitor Proteins

Many biological assays use antibodies to detect MyoD family inhibitor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MyoD family inhibitor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MyoD family inhibitor antibodies...

We validate the specificity of these antibodies to MyoD family inhibitor by testing them on tissues known to express MDFI positively and negatively. Browse below to find the MDFI antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MDFI Infographic by Boster Bio

MDFI protein infographic

All MDFI Products

Product

Figures

Specificity

Applications

Price

Anti-MyoD family inhibitor MDFI Antibody

3 Q&As

Human, Mouse

WB

$399
Cat # A10664-1
100μl

Anti-MDFI (P134) Antibody

Human, Mouse, Rat

IF, WB

$405
Cat # A10664
100ul

MDFI Overview

Facts about MyoD family inhibitor.

MDFI 3D structure

MDFI 3D structure. Source: alphafold

MyoD family inhibitor (MDFI)

Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals.

Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation.

Gene Information

Human
Gene Name:	MDFI
Uniprot:	Q99750
Entrez:	4188

Gene Information

Family

Belongs to:

MDFI family

Family

Alternative Names

I-MF; I-mfa; inhibitor of MyoD family a; MyoD family inhibitor; Myogenic repressor I-mf

Molecular Weight

Mass (kDA):
25.029 kDA

Molecular Weight

Genomic Context


Human

Location:	6p21.1
Sequence:	6; NC_000006.12 (41637018..41654246)

Subcellular Localizations

Nucleus. Cytoplasm.

Subcellular Localization

Diseases

Immunologic Deficiency Syndromes
Hiv Infections
Leukemia, T-cell
Carcinoma
Malignant Neoplasms
Neoplasms
Pancreatic Neoplasm
Malignant Neoplasm Of Pancreas
Leukemia
Non-neoplastic Disorder
Infarction
Myocardial Infarction

Cardiovascular Diseases
Tumor Angiogenesis
Headache
Cerebrovascular Accident
Pituitary Diseases
Htlv-i Infections

Disease

Pathways

Localization
Methylation
Nuclear Import
Neural Tube Closure
Cell Proliferation
Dna Methylation
Viral Genome Expression
Tube Closure
Axis Specification
Translation

Cell Differentiation
Angiogenesis
Viral Replication
Rna Interference

Pathways

PTMs

Phosphorylation

Methylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MDFI

References

PMID: 9250874 by Kraut N.; The gene encoding I-mf (Mdfi) maps to human chromosome 6p21 and mouse chromosome 17.

PMID: 17289077 by Wang Q., et al. Developmental regulators containing the I-mfa domain interact with T cyclins and Tat and modulate transcription.