MCMBP Antibodies

AND MCMBP ELISA kits, MCMBP Proteins

Many biological assays use antibodies to detect MCMBP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MCMBP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MCMBP antibodies...

We validate the specificity of these antibodies to MCMBP by testing them on tissues known to express MCMBP positively and negatively. Browse below to find the MCMBP antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MCMBP Infographic by Boster Bio

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Anti-MCMBP Antibody

Human, Mouse

$405
Cat # A08501
100ul

MCMBP Overview

Facts about Mini-chromosome maintenance complex-binding protein.

MCMBP 3D structure. Source: alphafold

Mini-chromosome maintenance complex-binding protein (MCMBP)

Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA.

Can dissociate the MCM complex without addition of ATP; likely acts by destabilizing interactions of every individual subunits of the MCM complex. Required for sister chromatid cohesion.

Gene Information

Human
Gene Name:	MCMBP
Uniprot:	Q9BTE3
Entrez:	79892

Family

Belongs to:

MCMBP family

Alternative Names

C10orf119; FLJ13081; MCM-binding protein; MCM-BP; minichromosome maintenance complex binding protein; mini-chromosome maintenance complex-binding protein; minichromosome maintenance complex-binding protein

Molecular Weight

Mass (kDA):
72.98 kDA

Genomic Context


Human

Location:	10q26.11
Sequence:	10; NC_000010.11 (119829404..119873628, complement)

Subcellular Localizations

Nucleus. Associates with chromatin. Highly associated with chromatin in G1/S and S phases, reduced binding to chromatin in G2, and further decreased binding in early M phase. It then reassociates with chromatin in late M phase. Dissociates from chromatin later than component of the MCM complex.