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- Table of Contents
Facts about Myc-associated zinc finger protein.
Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.
Human | |
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Gene Name: | MAZ |
Uniprot: | P56270 |
Entrez: | 4150 |
Belongs to: |
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No superfamily |
MAZI; MYC-associated zinc finger protein (purine-binding transcription factor); myc-associated zinc finger protein; PUR1; Pur-1SAF-2; Purine-binding transcription factor; serum amyloid A activating factor 1; serum amyloid A activating factor 2; Transcription factor Zif87; ZF87SAF-1; Zif87; Zinc finger protein 801; zinc-finger protein, 87 kilodaltons; ZNF801SAF-3
Mass (kDA):
48.608 kDA
Human | |
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Location: | 16p11.2 |
Sequence: | 16; NC_000016.10 (29806081..29811171) |
Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).
Nucleus. In brains of Alzheimer disease patients, present in a plaque-like structures.
PMID: 1502157 by Bossone S.A., et al. MAZ, a zinc finger protein, binds to c-MYC and C2 gene sequences regulating transcriptional initiation and termination.
PMID: 1567856 by Pyrc J.J., et al. Isolation of a novel cDNA encoding a zinc-finger protein that binds to two sites within the c-myc promoter.