Melanocortin receptor 5 Antibodies

AND MC5R ELISA kits, Melanocortin receptor 5 Proteins

Many biological assays use antibodies to detect Melanocortin receptor 5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Melanocortin receptor 5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Melanocortin receptor 5 antibodies...

We validate the specificity of these antibodies to Melanocortin receptor 5 by testing them on tissues known to express MC5R positively and negatively. Browse below to find the MC5R antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MC5R Infographic by Boster Bio

All MC5R Products

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Anti-MC5-R Antibody

7 Q&As

Human, Mouse, Rat

$399
Cat # A07019-1
100μl

Anti-MC5 Receptor Rabbit Monoclonal Antibody

Human

IHC, WB

$370
Cat # M07019
100 μl/vial

MC5R Overview

Facts about Melanocortin receptor 5.

MC5R 3D structure. Source: alphafold

Melanocortin receptor 5 (MC5R)

Receptor for MSH (alpha, beta and gamma) and ACTH.
The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

This receptor is a possible mediator of the immunomodulation properties of melanocortins. .

Gene Information

Human
Gene Name:	MC5R
Uniprot:	P33032
Entrez:	4161

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

MC2; MC-2; MC5; MC5R; MC5-R; melanocortin 5 receptor; melanocortin receptor 5; Melanocortin-5 R; melanocortin-5 receptor; Melanocortin5R; Melanocortin-5R

Molecular Weight

Mass (kDA):
36.601 kDA

Genomic Context


Human

Location:	18p11.21
Sequence:	18; NC_000018.10 (13824149..13827323)

Tissue Specificity

Expressed in the brain but not in the melanoma cells.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Obesity
Pituitary Diseases
Inflammation
Melanoma
Inflammatory Response
Nervousness
Hypertensive Disease
Malignant Neoplasms
Pain
Diabetes Mellitus
Physiological Stress

Neuralgia
Insulin Resistance
Cardiovascular Diseases
Cholangiocarcinoma
Malnutrition
Developmental Reading Disorder

Interacting Proteins

MRAP

Pathways

Energy Homeostasis
Pigmentation
Secretion
Localization
Inflammatory Response
Cytokine Production
Feeding Behavior
Response To Stress
Lactation
Immune Response
Neurogenesis
Eating Behavior

Metaphase
Conjugation
Regeneration
Reverse Transcription
Translation
Cell Death
Cell Cycle

PTMs

Phosphorylation
Acetylation
Cleavage

Amidation
Oxidation
Methylation

Iodination

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MC5R

References

PMID: 8396929 by Chhajlani V., et al. Molecular cloning of a novel human melanocortin receptor.

PMID: 8179577 by Griffon N., et al. Molecular cloning and characterization of the rat fifth melanocortin receptor.