Transcription factor MafG Antibodies

Transcription factor MafG (MAFG)

Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves (PubMed:11154691). However, they appear to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1 and NFE2L2, and recruiting them to particular DNA-binding sites (PubMed:8932385, PubMed:9421508, PubMed:11154691).

Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NFE2L2 transcription factor (PubMed:11154691). Transcription factor, part of erythroid-specific transcription factor NFE2L2 (PubMed:11154691).

Gene Information

Human
Gene Name:	MAFG
Uniprot:	O15525
Entrez:	4097

Family

Belongs to:
bZIP family

Alternative Names

basic leucine zipper transcription factor MafG; hMAF; MafG; MGC13090; MGC20149; transcription factor MafG; v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein G; v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian); V-maf musculoaponeurotic fibrosarcoma oncogene homolog G

Molecular Weight

Mass (kDA):
17.85 kDA

Genomic Context

Human
Location:	17q25.3
Sequence:	17; NC_000017.11 (81918270..81927735, complement)

Tissue Specificity

Highly expressed in skeletal muscle. Also expressed in heart and brain.

Subcellular Localizations

Nucleus.

Diseases

• Malignant Neoplasm Of Lung
• Malignant Neoplasms
• Neoplasms
• Lung Neoplasms
• Hypoxia
• Placental Choriocarcinoma
• Fibrosarcoma
• Injury To Liver
• Trophoblastic Neoplasms
• Nervousness
• Cell Transformation, Neoplastic
• Nerve Degeneration
• Nervous System Disorder

• Choriocarcinoma
• Hepatoblastoma
• Disease Of Adrenal Medulla
• Inflammatory Response
• Carcinogenesis
• Septic Shock
• Acute Erythroblastic Leukemia

Interacting Proteins

• BACH1
• NFE2L1
• NFE2L2
• NFE2L3

Pathways

• Localization
• Platelet Formation
• Cell Differentiation
• Oncogenesis
• Transport
• Cellular Homeostasis
• Response To Hypoxia
• Regulation Of Gene Expression
• Liver Development

• Inflammatory Response
• Startle Response
• Cell Cycle
• Pathogenesis

PTMs

• Sumoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAFG

Best Uses Of The MAFG Marker

The MAFG Marker is an antibody manufactured by Boster Bio. They are primarily known for their ELISA and signature products, but recently started providing molecular biology products related to PCR. Boster Bio also offers a variety of services for scientists and has 24 hour technical support. For more information, visit their website. To learn more, you can download their free technical resources and read the latest news from the company.

Benefits of using the MAFG Marker

In both cases, the MAFG Marker is a medical device designed to identify the tip of the catheter under fluoroscopy. The marker band is typically made of platinum iridium, although there are applications that call for gold or tantalum bands. It is attached to the catheter tip through swaging or embedding. The difference between the two processes lies in the method of attaching the marker band.

ELISA kit

Boster Bio has a rich history of providing antibodies and other reagents for research. In 1993, Steven Boster developed his first product. The name Boster came from his initials, Steven, which means "he who converts science in the lavatory." After developing hundreds of primary antibodies, Boster established one of the largest catalog antibody companies in China by the late nineties. Boster developed its own proprietary ELISA platform, PicoKine(tm) technology. This platform utilizes proprietary trade secrets to deliver incredibly sensitive, high-quality ELISA kits.

Boster Bio was founded in 1993 by renowned histologist Steven Xia. The company produces highly specific, highly sensitive ELISA kits and antibody reagents. Over 23,000 publications have cited their products, and Boster's reagents have undergone rigorous validation. Boster Quality GuaranteeTM provides peace of mind knowing that your research will be successful. Boster Bio has expanded its product lines monthly.

WB/IHC

The MAFG Marker is an ink pen with a polymer body. It is assembled by a machine, and the barrel contains a plastic plug. A needle is then inserted to inject the ink. The writing nib is then inserted in the same end of the barrel. A plastic cap is then placed on the marker, and the ink slowly transfers to the new writing tip. The MAFG Marker is an excellent choice for students and professionals alike, and is often the first option for creative artists.

While the placement of a fiducial marker may seem like an afterthought in PCB design, it is vital to the success of the entire manufacturing process. A great fiducial mark is essential to good manufacturing; a poor one leads to reprogramming and rework, and a poor one may cause significant quality issues. The Best Uses Of The MAFG Marker

Monoclonal antibody

The MAFG marker is a highly specific molecule that is widely used in many research applications. Its unique chemical structure allows it to recognize a wide variety of cell types and proteins, including mammalian cells. Its high sensitivity makes it an ideal choice for many applications, including gene therapy. The MAFG marker is also highly versatile, meaning that it can be used in a variety of different settings.

Agrisera: Agrisera produces monoclonal and polyclonal antibodies for a variety of applications. Their MAFG antibody kits are suitable for detection of a wide range of plant proteins. Its antibodies are highly reactive to over 2000 plant species and have been published in over 500 scientific journals. It has been praised as "the most innovative antibody supplier in plant science in 2018" and has developed proprietary ELISA platforms.

FANTOM5: This public database includes enhancer regions and CAGE tags from multiple species. Santa Cruz Biotechnology is a leading manufacturer of antibodies, biochemicals, and labware. Its Signal Recognition Particle Database (SRPDB) provides an integrated database of non-coding RNA sequences. It also contains an online encyclopedia of genes. Its Gene ORGANizer allows researchers to compare gene expression with the expression levels of organs.

Coating/capture: Coating/coating the microplates with an antigen-specific antibody allows for fine detection. Polymer-coated plates are also available to prevent nonspecific binding. A coating with less than maximum binding capacity prevents hooking, a phenomenon in which proteins become trapped between the coating proteins, preventing efficient washing of the unbound protein. The best-quality plates are able to detect antibodies to MAFG in as little as one day.