Lypd1 Antibodies

AND Lypd1 ELISA kits, Lypd1 Proteins

Many biological assays use antibodies to detect Lypd1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lypd1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lypd1 antibodies...

We validate the specificity of these antibodies to Lypd1 by testing them on tissues known to express Lypd1 positively and negatively. Browse below to find the Lypd1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Lypd1 Infographic by Boster Bio

All Lypd1 Products

Product

Figures

Specificity

Applications

Price

LYPD1 (NM_144586) Human Over-expression Lysate

Human

$628
Cat # LS116372
100 µg

Lypd1 Overview

Facts about Ly6/PLAUR domain-containing protein 1.

Ly6/PLAUR domain-containing protein 1 (Lypd1)

Believed to serve as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro raises receptor desensitization and decreases affinity for ACh of alpha- 4:beta-2-containing nAChRs (PubMed:19246390).

May play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7- containing nAChRs and may inhibit their expression at the cell surface (PubMed:26276394, PubMed:25716842). May be involved in the control of anxiety (PubMed:19246390).

Gene Information

Mouse
Gene Name:	Lypd1
Uniprot:	Q8BLC3
Entrez:	72585

Family

Belongs to:

No superfamily

Alternative Names

Ly6/PLAUR domain-containing protein 1

Molecular Weight

Mass (kDA):
15.261 kDA

Genomic Context


Mouse

Location:	1\|1 E3
Sequence:	1;

Tissue Specificity

Preferentially expressed in the nervous system. Expressed in embryonic and postnatal postmitotic central and peripheral neurons including subpopulations of motor neurons, sensory neurons, interneurons and neurons of the autonomous nervous system. Expressed around the growing nerves in the limb bud (PubMed:16236524). Expressed at high levels in specific brain regions such as the prefrontal cortex, amygdala, hippocampus, mediodorsal thalamus, dentate gyrus and specific brainstem nuclei (at protein level) (PubMed:19246390).

PTMs

Disulfide bond
Glycoprotein

GPI-anchor
Lipoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Lypd1

References

PMID: 16236524 by Dessaud E., et al. Identification of lynx2, a novel member of the ly-6/neurotoxin superfamily, expressed in neuronal subpopulations during mouse development.

PMID: 19246390 by Tekinay A.B., et al. A role for LYNX2 in anxiety-related behavior.