Lymphocyte antigen 96 Antibodies

AND Ly96 ELISA kits, Lymphocyte antigen 96 Proteins

Many biological assays use antibodies to detect Lymphocyte antigen 96, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lymphocyte antigen 96 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lymphocyte antigen 96 antibodies...

We validate the specificity of these antibodies to Lymphocyte antigen 96 by testing them on tissues known to express Ly96 positively and negatively. Browse below to find the Ly96 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: Lyar

Ly96 Infographic by Boster Bio

All Ly96 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-MD-2 LY96 Monoclonal Antibody [9F1B1]

Human, Mouse

ELISA, IF, IHC-P, WB

$524
Cat # M02107
0.1 mg

Anti-MD-2 LY96 Monoclonal Antibody [1A2E3]

Human, Mouse, Rat

ELISA, IF, IHC-P, ICC, WB

$524
Cat # M02107-1
0.1 mg

MD2 (LY96) (NM_001195797) Human Recombinant Protein

$1249
Cat # PROTQ9Y6Y9
20 µg

MD2 (LY96) (NM_015364) Human Over-expression Lysate

Human

$628
Cat # LS023643
100 µg

Human MD2 ELISA Kit PicoKine®

Human

ELISA

$499
Cat # EK2280
96 wells/kit, with removable strips.

Ly96 Overview

Facts about Lymphocyte antigen 96.

Lymphocyte antigen 96 (Ly96)

Binds bacterial lipopolysaccharide (LPS) (PubMed:22532668). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components in Gram-positive and Gram- negative bacteria.

Enhances TLR4-dependent activation of NF-kappa- B. Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS (PubMed:10725698).

Gene Information

Mouse
Gene Name:	Ly96
Uniprot:	Q9JHF9
Entrez:	17087

Family

Belongs to:

No superfamily

Alternative Names

ESOP1; ESOP-1; LY96; ly-96; lymphocyte antigen 96; MD2; MD-2; myeloid differentiation protein-2; Protein MD-2

Molecular Weight

Mass (kDA):
18.394 kDA

Genomic Context


Mouse

Location:	1\|1 A3
Sequence:	1;

Tissue Specificity

Highly expressed in spleen, bone marrow, thymus, liver, kidney, ovary and decidua. Detected at lower levels in testis, small intestine and skin.

Diseases

Inflammation
Systemic Infection
Innate Immune Response
Inflammatory Response
Malignant Neoplasms
Infective Disorder
Septic Shock
Bacterial Infections
Salmonella Infections
Pneumonia
Neoplasms
Atherosclerosis
Cell Invasion

Tissue Adhesions
Gram-negative Bacterial Infections
Communicable Diseases
Tissue Damage
Corneal Diseases
Fibrosis
Colitis

Pathways

Immune Response
Secretion
Inflammatory Response
Innate Immune Response
Cell Activation
Cytokine Production
Pathogenesis
Response To Lipopolysaccharide
Localization
Virulence
Glycosylation
Cytokine Secretion
Phagocytosis

Transport
Reverse Transcription
Endocytosis
Cell Differentiation
Cell Proliferation
Macrophage Activation
Cell Death

PTMs

Phosphorylation
Glycosylation
Acylation
Biotinylation
Cleavage
Carboxylation

Ubiquitination
Acetylation
Oxidation
Methylation
Palmitoylation
Deglycosylation

Myristoylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ly96

References

PMID: 10891475 by Kato K., et al. ESOP-1, a secreted protein expressed in the hematopoietic, nervous, and reproductive systems of embryonic and adult mice.

PMID: 10725698 by Akashi S., et al. Cell surface expression and lipopolysaccaride signaling via the Toll- like receptor 4-MD-2 complex on mouse peritoneal macrophages.