LTK Antibodies

AND LTK ELISA kits, LTK Proteins

Many biological assays use antibodies to detect LTK, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LTK in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LTK antibodies...

We validate the specificity of these antibodies to LTK by testing them on tissues known to express LTK positively and negatively. Browse below to find the LTK antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LTK Infographic by Boster Bio

All LTK Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-LTK Antibody Picoband®

3 Q&As

Human

$370
Cat # PA1990
100 μg/vial

Anti-LTK Antibody

Human, Mouse

$360
Cat # A04217
100 µl

LTK Colorimetric Cell-Based ELISA

Human, Mouse

ELISA

$480
Cat # EKC1704
1 kit, containing one 96-well plate and all necessary reagents

LTK (NM_002344) Human Recombinant Protein

$1249
Cat # PROTP29376
20 µg

Anti-LTK Rabbit Monoclonal Antibody

Human

IHC, WB

$370
Cat # M04217
100 μl/vial

LTK (NM_002344) Human Over-expression Lysate

Human

$960
Cat # LS004058
100 µg

Human LTK ELISA Kit PicoKine®

Human

ELISA

$750
Cat # EK2241
96 wells/kit, with removable strips.

LTK Overview

Facts about Leukocyte tyrosine kinase receptor.

LTK 3D structure. Source: alphafold

Leukocyte tyrosine kinase receptor (LTK)

Receptor using a tyrosine-protein kinase activity. The exact function of this protein is not known.

Studies with chimeric proteins (substituting its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway.

Gene Information

Human
Gene Name:	LTK
Uniprot:	P29376
Entrez:	4058

Family

Belongs to:

protein kinase superfamily

Alternative Names

EC 2.7.10.1; leukocyte receptor tyrosine kinase; leukocyte tyrosine kinase receptor; leukocyte tyrosine kinase; LTK; TYK1; TYK1Protein tyrosine kinase 1

Molecular Weight

Mass (kDA):
91.681 kDA

Genomic Context


Human

Location:	15q15.1
Sequence:	15; NC_000015.10 (41503637..41513887, complement)

Tissue Specificity

Expressed in non-hematopoietic cell lines and T- and B-cell lines.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Corneal Diseases
Hyperopia
Lymphoma
Refractive Errors
Myopia
Anaplastic Lymphoma
Nervousness
Malignant Neoplasms
Neoplasms
Parkinson Disease
Malignant Paraganglionic Neoplasm
Chromosomal Translocation

Neuroblastoma
Hyperplasia
T(2;5)(p23;q35)
Inflammation
Hypoxia
Patient Dependence On

Interacting Proteins

ALKAL1

Pathways

Coagulation
Localization
Cell Growth
Pathogenesis
Transport
Translation
Wound Healing
Proteolysis
Gene Conversion
Sensitization
System Development
Vasoconstriction
Dopamine Uptake

Methylation
Cell Death
Secretion
Protein Phosphorylation
Endoplasmic Reticulum Localization
Hyperphosphorylation
Regulation Of Signaling

PTMs

Phosphorylation
Glycosylation
Biotinylation
Cleavage

Methylation
Reduction
Dephosphorylation
Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LTK

References

PMID: 7685902 by Toyoshima H., et al. Differently spliced cDNAs of human leukocyte tyrosine kinase receptor tyrosine kinase predict receptor proteins with and without a tyrosine kinase domain and a soluble receptor protein.

PMID: 1655406 by Krolewski J.J., et al. The ltk gene encodes a novel receptor-type protein tyrosine kinase.