LPCAT1 Antibodies

AND LPCAT1 ELISA kits, LPCAT1 Proteins

Many biological assays use antibodies to detect LPCAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LPCAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LPCAT1 antibodies...

We validate the specificity of these antibodies to LPCAT1 by testing them on tissues known to express LPCAT1 positively and negatively. Browse below to find the LPCAT1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LPCAT1 Infographic by Boster Bio

All LPCAT1 Products

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Product

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Specificity

Applications

Price

Anti-LPCAT1 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A04863
100ul

LPCAT1 (NM_024830) Human Recombinant Protein

$1062
Cat # PROTQ8NF37
20 µg

LPCAT1 (NM_024830) Human Over-expression Lysate

Human

$960
Cat # LS079888
100 µg

LPCAT1 Overview

Facts about Lysophosphatidylcholine acyltransferase 1.

LPCAT1 3D structure. Source: alphafold

Lysophosphatidylcholine acyltransferase 1 (LPCAT1)

Possesses both acyltransferase and acetyltransferase activities (PubMed:16864775, PubMed:21498505). Action is calcium-independent (By similarity).

Mediates the conversion of 1- acyl-sn-glycero-3-phosphocholine (LPC) to phosphatidylcholine (PC) (PubMed:21498505). Displays a definite preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (PubMed:16704971).

Gene Information

Human
Gene Name:	LPCAT1
Uniprot:	Q8NF37
Entrez:	79888

Family

Belongs to:

1-acyl-sn-glycerol-3-phosphate acyltransferase family

Alternative Names

1-acylglycerophosphocholine O-acyltransferase; Acetyl-CoA:lyso-PAF acetyltransferase; Acetyl-CoA:lyso-platelet-activating factor acetyltransferase; acyl-CoA:lysophosphatidylcholine acyltransferase 1; acyltransferase like 2; Acyltransferase-like 2; AYTL2; EC 2.3.1.-; EC 2.3.1.23,1-alkylglycerophosphocholine O-acetyltransferase; EC 2.3.1.67; FLJ12443; FLJ41609; LPC acyltransferase 1; lpcat; LPCAT-1; Lyso-PAF acetyltransferase; lysoPAFAT; LysoPC acyltransferase 1; lysophosphatidylcholine acyltransferase 1; PFAAP3; Phosphonoformate immuno-associated protein 3; regulated by phosphonoformate

Molecular Weight

Mass (kDA):
59.151 kDA

Genomic Context


Human

Location:	5p15.33
Sequence:	5; NC_000005.10 (1461427..1523960, complement)

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Lipid droplet. May adopt a monotopic topology when embedded in the lipid monolayer of the lipid droplet, with both termini exposed to the cytoplasm.

Diseases

Inflammation
Sclerosis
Malignant Neoplasms
Neoplasms
Retinal Diseases
Respiratory Distress Syndrome, Newborn
Respiratory Distress
Multiple Sclerosis
Pneumonia
Retinal Dystrophies
Amaurosis

Neoplasm Metastasis
Intraepithelial Neoplasia
Spinal Cord Injuries
Peripheral Nerve Injuries
Malignant Tumor Of Colon

Pathways

Localization
Reverse Transcription
Transport
Response To Stress
Lung Development
Defense Response
Seed Development
Lipid Homeostasis
Cell Redox Homeostasis

Pathogenesis
Surfactant Homeostasis
Nuclear Import
Secretion

PTMs

Phosphorylation
Oxidation

Ribosylation
Palmitoylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LPCAT1

References

PMID: 16704971 by Nakanishi H., et al. Cloning and characterization of mouse lung-type acyl- CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1): expression in alveolar type II cells and possible involvement in surfactant production.

PMID: 12693554 by Jikuya H., et al. Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones.