KRT1 Antibodies

AND KRT1 ELISA kits, KRT1 Proteins

Many biological assays use antibodies to detect KRT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KRT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KRT1 antibodies...

We validate the specificity of these antibodies to KRT1 by testing them on tissues known to express KRT1 positively and negatively. Browse below to find the KRT1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KRT1 Infographic by Boster Bio

All KRT1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PCK Antibody (Monoclonal, C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2)

3 Citations 7 Q&As

Human, Rat

IHC, WB

$370
Cat # MA1081
100 μg/vial

Anti-Cytokeratin 1 Rabbit Monoclonal Antibody

2 Citations

Human, Mouse, Rat

IHC, WB

$370
Cat # M01639-1
100 μl

Anti-Cytokeratin 1 Rabbit Monoclonal Antibody

2 Citations

Human, Mouse, Rat

$370
Cat # M01639
100 μl

Anti-Cytokeratin 1/KRT1 Antibody Picoband®

Human

ELISA, Flow Cytometry, IF, IHC, WB

$370
Cat # A01639
100 µg/vial

Anti-Cytokeratin 1/Krt1 Antibody Picoband®

Mouse

ELISA, IF, IHC, WB

$370
Cat # A01639-1
100 µg/vial

KRT1 Overview

Facts about Keratin, type II cytoskeletal 1.

KRT1 3D structure. Source: alphafold

Keratin, type II cytoskeletal 1 (KRT1)

May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.

Gene Information

Human
Gene Name:	KRT1
Uniprot:	P04264
Entrez:	3848

Family

Belongs to:

intermediate filament family

Alternative Names

CK1; CK-1; cytokeratin 1; Cytokeratin-1; cytokeratin-1,67 kDa cytokeratin; EHK; EHK1; epidermolytic hyperkeratosis 1; EPPK; Hair alpha protein; K1; keratin 1; keratin, type II cytoskeletal 1; Keratin-1; KRT1A; KRTA; NEPPK; Type-II keratin Kb1

Molecular Weight

Mass (kDA):
66.039 kDA

Genomic Context


Human

Location:	12q13.13
Sequence:	12; NC_000012.12 (52674736..52680407, complement)

Tissue Specificity

The source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis.

Subcellular Localizations

Cell membrane. Located on plasma membrane of neuroblastoma NMB7 cells.

Diseases

Bullous Congenital Ichthyosiform Erythroderma (disorder)
Hyperkeratosis
Palmoplantar Keratosis
Ichthyoses
Exfoliative Dermatitis
Ichthyosiform Erythroderma, Congenital
Bulla
Keratoderma, Palmoplantar, Epidermolytic
Carcinoma
Skin Diseases, Genetic
Dermatologic Disorders

Neoplasms
Malignant Squamous Cell Neoplasm
Erythema
Skin Neoplasms
Malignant Neoplasms
Keratoderma, Palmoplantar, Diffuse

Interacting Proteins

GOLGA2
KRT15
KRT33B
NUP62
TRIM27

Pathways

Keratinocyte Differentiation
Keratinization
Translation
Wound Healing
Cornification
Dna Methylation
Methylation
Pathogenesis
Cell Migration
Response To Peptidoglycan
Aging
Fertilization
Skin Development

Pigmentation
Intermediate Filament Organization
Tissue Development
Cell Cycle
Anagen
Cell-cell Adhesion
Cell Proliferation

PTMs

Methylation

Cleavage

Research Areas

Cell Biology
Cellular Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KRT1

References

PMID: 2580302 by Johnson L.D., et al. Structure of a gene for the human epidermal 67-kDa keratin.

PMID: 10903910 by Whittock N.V., et al. Genomic organization and amplification of the human epidermal type II keratin genes K1 and K5.

3 Publications of Boster KRT1 Antibodies & ELISA Kits

PubMed ID: 26870216, A metanephric adenoma of the kidney associated with polycythemia: A case report
PubMed ID: 24962416, Stanniocalcin-1 protects bovine intestinal epithelial cells from oxidative stres...
PubMed ID: 23185403, Bai J, Liu H, Li D, Cui L, Wu X. Plos One. 2012;7(11):E49673. Doi: 10.1371/Journ...

*More publications can be found for each product on its corresponding product page