Kremen protein 2 Antibodies

AND Kremen2 ELISA kits, Kremen protein 2 Proteins

Many biological assays use antibodies to detect Kremen protein 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Kremen protein 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Kremen protein 2 antibodies...

We validate the specificity of these antibodies to Kremen protein 2 by testing them on tissues known to express Kremen2 positively and negatively. Browse below to find the Kremen2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Kremen2 Infographic by Boster Bio

All Kremen2 Products

Product

Figures

Specificity

Applications

Price

Anti-Kremen protein 2 KREMEN2 Antibody

Human, Mouse, Rat

ELISA, ICC, WB

$449
Cat # A11875
0.1 mg

KREMEN2 (NM_024507) Human Recombinant Protein

$1249
Cat # PROTQ8NCW0
20 µg

KREMEN2 (NM_024507) Human Over-expression Lysate

Human

$628
Cat # LS079412
100 µg

Kremen2 Overview

Facts about Kremen protein 2.

Kremen protein 2 (Kremen2)

Receptor for Dickkopf proteins.
Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by boosting the endocytosis of Wnt receptors LRP5 and LRP6 (PubMed:12050670).

Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning and can also negatively regulate bone formation (PubMed:18505822). .

Gene Information

Mouse
Gene Name:	Kremen2
Uniprot:	Q8K1S7
Entrez:	73016

Family

Belongs to:

No superfamily

Alternative Names

Dickkopf receptor 2; kremen protein 2; Kremen2; Kremen-2; kringle containing transmembrane protein 2; Kringle domain-containing transmembrane protein 2; KRM2Kringle-containing protein marking the eye and the nose; MGC10791; MGC16709

Molecular Weight

Mass (kDA):
49.17 kDA

Genomic Context


Mouse

Location:	17\|17 A3.3
Sequence:	17;

Diseases

Multiple Myeloma
Malignant Neoplasms
Colorectal Cancer
Limb Deformities, Congenital
Cell Invasion
Malignant Neoplasm Of Gastrointestinal Tract
Microcephaly
Neoplasm Metastasis
Cell Transformation, Neoplastic
Metastatic Malignant Neoplasm To The Lymph Node
Limb Defect
Gastrointestinal Neoplasms

Tissue Adhesions
Neoplasm Invasiveness
Fracture
Nervousness
Colorectal Neoplasms
Mammary Neoplasms
Osteoporosis

Pathways

Osteoblast Differentiation
Cell Growth
Endocytosis
Methylation
Cell Adhesion
Cell Proliferation
Gastrulation
Translation
Immune Response

Regulation Of Gene Expression
Pathogenesis
Limb Development

PTMs

Demethylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Kremen2

References

PMID: 12050670 by Mao B., et al. Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling.

PMID: 16531414 by Cruciat C.-M., et al. The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition.