Krueppel-like factor 10 Antibodies

AND KLF10 ELISA kits, Krueppel-like factor 10 Proteins

Many biological assays use antibodies to detect Krueppel-like factor 10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Krueppel-like factor 10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Krueppel-like factor 10 antibodies...

We validate the specificity of these antibodies to Krueppel-like factor 10 by testing them on tissues known to express KLF10 positively and negatively. Browse below to find the KLF10 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KLF10 Infographic by Boster Bio

All KLF10 Products

Product

Figures

Specificity

Applications

Price

Anti-KLF10/KLF11 Antibody

Human, Mouse, Rat

$405
Cat # A03419
100ul

Anti-TIEG-1/2 KLF10 Antibody

1 Citations

Human, Mouse, Rat

ELISA, IHC

$380
Cat # A03419-1
100ul

Anti-KLF10 Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M03419
100 μl/vial

Anti-KLF10 Antibody Picoband™

Human

ELISA, IF, ICC, WB

$370
Cat # A03419-2
100 μg/vial

KLF10 (NM_005655) Human Over-expression Lysate

Human

$628
Cat # LS007071
100 µg

KLF10 Overview

Facts about Krueppel-like factor 10.

KLF10 3D structure. Source: alphafold

Krueppel-like factor 10 (KLF10)

Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the center clock component ARTNL/BMAL1 and represses its transcriptional activity.

Regulates the circadian expression of enzymes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity).

Gene Information

Human
Gene Name:	KLF10
Uniprot:	Q13118
Entrez:	7071

Family

Belongs to:

Sp1 C2H2-type zinc-finger protein family

Alternative Names

EGRA; EGR-alpha; KLF10; Krueppel-like factor 10; Kruppel-like factor 10; TGFB inducible early growth response; TGFB-inducible early growth response protein 1; TIEG1; TIEG-1; TIEG1TIEG; Transforming growth factor-beta-inducible early growth response protein 1

Molecular Weight

Mass (kDA):
52.555 kDA

Genomic Context


Human

Location:	8q22.3
Sequence:	8; NC_000008.11 (102648777..102655725, complement)

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Malignant Neoplasm Of Pancreas
Malignant Neoplasm Of Breast
Cell Transformation, Neoplastic
Inflammation
Hypertrophy
Mammary Neoplasms
Pancreatic Neoplasm
Adenocarcinoma
Atherosclerosis
Neoplasm Metastasis

Carcinogenesis
Malignant Paraganglionic Neoplasm
Prostatic Neoplasms
Cell Invasion
Malignant Neoplasm Of Prostate
Osteoporosis
Diabetes Mellitus

Interacting Proteins

Pathways

Cell Proliferation
Cell Cycle
Cell Growth
Cell Death
Cell Differentiation
Localization
Pathogenesis
Osteoclast Differentiation
Cell Cycle Arrest
Regulation Of Gene Expression
Translation
G1 Phase
Methylation

Regulation Of Cell Proliferation
Angiogenesis
Muscle Cell Proliferation
Cell Activation
Osteoblast Differentiation
T Cell Activation
Immune Response

PTMs

Phosphorylation
Methylation
Demethylation

Cleavage
Acetylation
Ubiquitination

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KLF10

References

PMID: 8584037 by Blok L.J., et al. Characterization of an early growth response gene, which encodes a zinc finger transcription factor, potentially involved in cell cycle regulation.

PMID: 8532536 by Subramaniam M., et al. Identification of a novel TGF-beta-regulated gene encoding a putative zinc finger protein in human osteoblasts.

1 Publications of Boster Krueppel-like factor 10 Antibodies & ELISA Kits

PubMed ID: 32156482, Zheng L,Lu H,Li H,Xu X,Wang D.KLF10 is upregulated in osteoarthritis and inhibit...

*More publications can be found for each product on its corresponding product page