Nucleolysin TIAR Antibodies

AND TIAL1 ELISA kits, Nucleolysin TIAR Proteins

Many biological assays use antibodies to detect Nucleolysin TIAR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nucleolysin TIAR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nucleolysin TIAR antibodies...

We validate the specificity of these antibodies to Nucleolysin TIAR by testing them on tissues known to express TIAL1 positively and negatively. Browse below to find the TIAL1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TIAL1 Infographic by Boster Bio

All TIAL1 Products

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Specificity

Applications

Price

Anti-Nucleolysin TIAR TIAL1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A05600
100ul

Human TIAL1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ01085
Starting from 20ug

TIAL1 (NM_003252) Human Over-expression Lysate

Human

$628
Cat # LS007073
100 µg

TIAL1 Overview

Facts about Nucleolysin TIAR.

TIAL1 3D structure. Source: alphafold

Nucleolysin TIAR (TIAL1)

RNA-binding protein. Possesses nucleolytic activity against cytotoxic lymphocyte target cells.

May be involved in apoptosis. .

Gene Information

Human
Gene Name:	TIAL1
Uniprot:	Q01085
Entrez:	7073

Family

Belongs to:

No superfamily

Alternative Names

aging-associated gene 7 protein; MGC33401; TCBP; T-cluster binding protein; TIA1 cytotoxic granule-associated RNA binding protein-like 1; TIA1 cytotoxic granule-associated RNA-binding protein-like 1; TIA-1 related protein; TIA-1-related nucleolysin; TIA-1-related protein; TIARnucleolysin TIAR

Molecular Weight

Mass (kDA):
41.591 kDA

Genomic Context


Human

Location:	10q26.11
Sequence:	10; NC_000010.11 (119573465..119598841, complement)

Subcellular Localizations

Cytoplasm. Nucleus. Cytoplasmic granule. The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Colocalizes with NANOS3 in the stress granules (By similarity). Cytoplasmic granules of cytolytic T-lymphocytes.

Diseases

Transient Ischemic Attack
Malignant Neoplasms
Neoplasms
Infective Disorder
Lymphoma
T-cell Lymphoma
Virus Diseases
Atrophy
Stomach Neoplasms
Brain Ischemia
Carcinoma
Ischemia

Physiological Stress
Inflammation
Autoimmune Reaction
Hypoxia
Infertility
Tumor Angiogenesis
Spinal Muscular Atrophy

Pathways

Translation
Localization
Cell Death
Cell Proliferation
Immune Response
Rna Processing
Pathogenesis
Transport
Cell Activation
Regulation Of Gene Expression
Rna Stabilization
Reverse Transcription
Mrna Stabilization

Response To Stress
Cell Development
Germ Cell Development
Angiogenesis
Rna Interference
Response To Lipopolysaccharide
Cell Adhesion

PTMs

Phosphorylation
Biotinylation

Cleavage
Dephosphorylation

Ubiquitination

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TIAL1

References

PMID: 1326761 by Kawakami A., et al. Identification and functional characterization of a TIA-1-related nucleolysin.

PMID: 20932473 by Reinhardt H.C., et al. DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization.