KIR2DS4 Antibodies

AND KIR2DS4 ELISA kits, KIR2DS4 Proteins

Many biological assays use antibodies to detect KIR2DS4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KIR2DS4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KIR2DS4 antibodies...

We validate the specificity of these antibodies to KIR2DS4 by testing them on tissues known to express KIR2DS4 positively and negatively. Browse below to find the KIR2DS4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KIR2DS4 Infographic by Boster Bio

All KIR2DS4 Products

Product

Figures

Specificity

Applications

Price

Anti-KIR2DS4 Antibody

Human

IF, WB

$405
Cat # A04052
100ul

Human KIR2DS4/CD158i Recombinant Protein

SDS-PAGE

$265
Cat # PROTP43632
Starting from 20ug

KIR2DS4 Overview

Facts about Killer cell immunoglobulin-like receptor 2DS4.

KIR2DS4 3D structure. Source: alphafold

Killer cell immunoglobulin-like receptor 2DS4 (KIR2DS4)

Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.

Gene Information

Human
Gene Name:	KIR2DS4
Uniprot:	P43632
Entrez:	3809

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

CD158 antigen-like family member I; CD158i antigen; CD158i; cl-39; killer cell immunoglobulin-like receptor 2DS4; killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail4,nkat8; killer inhibitory receptor 4-1-2; KIR antigen 2DS4; KIR2DS4; KKA3KIR1D; MGC120019; MGC125315; MGC125317; MHC class I NK cell receptor; natural killer cell inhibitory receptor; Natural killer-associated transcript 8; NKAT-8; NKAT8KIR412; P58 natural killer cell receptor clones CL-39/CL-17; p58 NK receptor CL-39/CL-17

Molecular Weight

Mass (kDA):
33.583 kDA

Genomic Context


Human

Location:	19q13.42
Sequence:	19; NC_000019.10 (54832707..54848575)

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Dysequilibrium Syndrome
Neoplasms
Leukemia
Graft-vs-host Disease
Myeloid Leukemia, Chronic
Acute Gvh Disease
Virus Diseases
Carcinoma
Cytomegalovirus Infections
Malaria
Psoriasis
Hepatitis

Infective Disorder
Acute Lymphocytic Leukemia
Sclerosis
Intraepithelial Neoplasia
Melanoma
Hepatitis B

Interacting Proteins

HLA-F

Pathways

Pathogenesis
Cell Activation
Immune Response
Methylation
Gene Conversion
Cytolysis

Interferon-gamma Production

PTMs

Deglycosylation

Biotinylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KIR2DS4

References

PMID: 7749980 by Wagtmann N., et al. Molecular clones of the p58 NK cell receptor reveal immunoglobulin- related molecules with diversity in both the extra- and intracellular domains.

PMID: 8662091 by Doehring C., et al. Alternatively spliced forms of human killer inhibitory receptors.