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- Table of Contents
Facts about UPF0577 protein KIAA1324.
Human | |
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Gene Name: | KIAA1324 |
Uniprot: | Q6UXG2 |
Entrez: | 57535 |
Belongs to: |
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UPF0577 family |
estrogen-induced gene 121 protein; hypothetical protein LOC57535; KIAA1324; MGC150624
Mass (kDA):
111.382 kDA
Human | |
---|---|
Location: | 1p13.3 |
Sequence: | 1; NC_000001.11 (109114106..109206781) |
Expressed in normal endometrium but overexpressed in endometroid tumors.
Cell membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass membrane protein.
PMID: 16322283 by Deng L., et al. Identification of a novel estrogen-regulated gene, EIG121, induced by hormone replacement therapy and differentially expressed in type I and type II endometrial cancer.
PMID: 21072319 by Deng L., et al. The novel estrogen-induced gene EIG121 regulates autophagy and promotes cell survival under stress.