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- Table of Contents
Facts about Lysine-specific demethylase 4D.
Demethylates both di- and trimethylated H3'Lys- 9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue creates formaldehyde and succinate.
Human | |
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Gene Name: | KDM4D |
Uniprot: | Q6B0I6 |
Entrez: | 55693 |
Belongs to: |
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JHDM3 histone demethylase family |
EC 1.14.11; EC 1.14.11.-; FLJ10251; JHDM3D; JmjC domain-containing histone demethylation protein 3D; JMJD2Dlysine-specific demethylase 4D; jumonji domain containing 2D; Jumonji domain-containing protein 2D; lysine (K)-specific demethylase 4D; MGC141909
Mass (kDA):
58.603 kDA
Human | |
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Location: | 11q21 |
Sequence: | 11; NC_000011.10 (94973709..94999519) |
Nucleus.
PMID: 15138608 by Katoh M., et al. Identification and characterization of JMJD2 family genes in silico.
PMID: 16603238 by Whetstine J.R., et al. Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.