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- Table of Contents
Facts about Potassium channel subfamily K member 5.
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Human | |
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Gene Name: | KCNK5 |
Uniprot: | O95279 |
Entrez: | 8645 |
Belongs to: |
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two pore domain potassium channel (TC 1.A.1.8) family |
Acid-sensitive potassium channel protein TASK-2; FLJ11035; K2p5.1; potassium channel subfamily K member 5; potassium channel, subfamily K, member 1 (TASK-2); potassium channel, subfamily K, member 5; TASK-2; TASK2K2P5.1 potassium channel; TWIK-related acid-sensitive K(+) channel 2; TWIK-related acid-sensitive K+ channel 2
Mass (kDA):
55.13 kDA
Human | |
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Location: | 6p21.2 |
Sequence: | 6; NC_000006.12 (39188971..39229475, complement) |
Abundant expression in kidney, also detected in liver, placenta and small intestine. In the kidney, expression is restricted to the distal tubules and collecting ducts. Not expressed in proximal tubules or glomeruli.
Membrane; Multi-pass membrane protein.
PMID: 9812978 by Reyes R., et al. Cloning and expression of a novel pH-sensitive two pore domain K+ channel from human kidney.
PMID: 18516069 by Gierten J., et al. Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein.