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- Table of Contents
3 Q&As
Facts about G protein-activated inward rectifier potassium channel 3.
Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium (By similarity).
Human | |
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Gene Name: | KCNJ9 |
Uniprot: | Q92806 |
Entrez: | 3765 |
Belongs to: |
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inward rectifier-type potassium channel (TC 1.A.2.1) family |
G protein-activated inward rectifier potassium channel 3; G protein-coupled inward rectifier potassium channel; GIRK-3; GIRK3KIR3.3; Inward rectifier K(+) channel Kir3.3; inwardly rectifier K+ channel KIR3.3; Kir3.3; Potassium channel, inwardly rectifying subfamily J member 9; potassium inwardly-rectifying channel, subfamily J, member 9
Mass (kDA):
44.02 kDA
Human | |
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Location: | 1q23.2 |
Sequence: | 1; NC_000001.11 (160081538..160090563) |
Membrane; Multi-pass membrane protein.
PMID: 10659995 by Schoots O., et al. Co-expression of human Kir3 subunits can yield channels with different functional properties.
PMID: 10913335 by Vaughn J., et al. Genomic structure and expression of human KCNJ9 (Kir3.3/GIRK3).