KCNJ16 Antibodies

AND KCNJ16 ELISA kits, KCNJ16 Proteins

Many biological assays use antibodies to detect KCNJ16, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCNJ16 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCNJ16 antibodies...

We validate the specificity of these antibodies to KCNJ16 by testing them on tissues known to express KCNJ16 positively and negatively. Browse below to find the KCNJ16 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KCNJ16 Infographic by Boster Bio

All KCNJ16 Products

Product

Figures

Specificity

Applications

Price

Anti-Kir5.1 (Ab-416) KCNJ16 Antibody

Human

IF, IHC, WB

$360
Cat # A10858
100 µl

Anti-KIR5.1 KCNJ16 Antibody

7 Q&As

Human, Mouse, Rat

$399
Cat # A10858-1
100μl

Anti-Kir5.1 (N410) KCNJ16 Antibody

Mouse, Rat

IF, IHC, WB

$405
Cat # A10858-2
100ul

Anti-Phospho-KIR5.1 (S416) KCNJ16 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A10858S416
100ul

Anti-KCNJ16 Antibody Picoband™

Human, Monkey

Flow Cytometry, WB

$370
Cat # A10858-3
100 μg/vial

KIR5.1 (KCNJ16) (NM_018658) Human Over-expression Lysate

Human

$628
Cat # LS003773
100 µg

KCNJ16 Overview

Facts about Inward rectifier potassium channel 16.

KCNJ16 3D structure. Source: alphafold

Inward rectifier potassium channel 16 (KCNJ16)

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.

The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance.

Gene Information

Human
Gene Name:	KCNJ16
Uniprot:	Q9NPI9
Entrez:	3773

Family

Belongs to:

inward rectifier-type potassium channel (TC 1.A.2.1) family

Alternative Names

BIR9; Inward rectifier K(+) channel Kir5.1; inward rectifier K+ channel KIR5.1; inward rectifier potassium channel 16; Kir5.1; MGC33717; Potassium channel, inwardly rectifying subfamily J member 16; potassium inwardly-rectifying channel, subfamily J, member 16

Molecular Weight

Mass (kDA):
47.949 kDA

Genomic Context


Human

Location:	17q24.3
Sequence:	17; NC_000017.11 (70075225..70135608)

Tissue Specificity

Widely expressed, with highest levels in adult and fetal kidney (at protein level). In the kidney, expressed in the proximal and distal convoluted tubules, but not in glomeruli nor collecting ducts.

Subcellular Localizations

Membrane; Multi-pass membrane protein. Basolateral cell membrane. In kidney distal convoluted tubules, located in the basolateral membrane in the presence of KCNJ10.

Diseases

Acidosis
Ataxia
Metabolic Acidosis
Hypercapnia
Alkalosis
Complete Hearing Loss
Acidosis, Respiratory
Sensorineural Hearing Loss (disorder)
Adenoma
Metabolic Alkalosis
Parathyroid Neoplasms
Hypoxia

Carcinoma
Body Dysmorphic Disorders
Malignant Neoplasms
Bartter Disease
Cerebrovascular Accident
Parathyroid Gland Adenoma
Parathyroid Gland Adenocarcinoma

Pathways

Transport
Ion Transport
Pathogenesis
Localization
Excretion

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCNJ16

References

PMID: 11060447 by Liu Y., et al. The human inward rectifier K(+) channel subunit kir5.1 (KCNJ16) maps to chromosome 17q25 and is expressed in kidney and pancreas.

PMID: 11240146 by Derst C., et al. Genetic and functional linkage of Kir5.1 and Kir2.1 channel subunits.