KCNG3 Antibodies

AND KCNG3 ELISA kits, KCNG3 Proteins

Many biological assays use antibodies to detect KCNG3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCNG3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCNG3 antibodies...

We validate the specificity of these antibodies to KCNG3 by testing them on tissues known to express KCNG3 positively and negatively. Browse below to find the KCNG3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KCNG3 Infographic by Boster Bio

All KCNG3 Products

Product

Figures

Specificity

Applications

Price

Anti-KCNG3 Antibody

Human, Mouse, Rat

$405
Cat # A10593-1
100ul

KCNG3 (NM_133329) Human Over-expression Lysate

Human

$628
Cat # LS170850
100 µg

KCNG3 Overview

Facts about Potassium voltage-gated channel subfamily G member 3.

KCNG3 3D structure. Source: alphafold

Potassium voltage-gated channel subfamily G member 3 (KCNG3)

Potassium channel subunit that doesn't form functional channels by itself (PubMed:11852086). Can form functional heterotetrameric channels with KCNB1; this promotes a reduction in the rate of activation and inactivation of the delayed rectifier voltage-gated potassium channel KCNB1 (PubMed:11852086, PubMed:19074135).

Gene Information

Human
Gene Name:	KCNG3
Uniprot:	Q8TAE7
Entrez:	170850

Family

Belongs to:

potassium channel family

Alternative Names

KV10.1; KV6.3; potassium voltage-gated channel subfamily G member 3; potassium voltage-gated channel, subfamily G, member 3; voltage-gated potassium channel 6.3; voltage-gated potassium channel Kv10.1; Voltage-gated potassium channel subunit Kv10.1; Voltage-gated potassium channel subunit Kv6.3; voltage-gated potassium channel subunit Kv6.4

Molecular Weight

Mass (kDA):
49.593 kDA

Genomic Context


Human

Location:	2p21
Sequence:	2; NC_000002.12 (42442017..42493982, complement)

Tissue Specificity

Expressed in the brain, liver, testis, small intestine, colon, thymus and adrenal gland (PubMed:11852086, PubMed:12060745).

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cytoplasm. Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane (PubMed:12060745). Colocalizes with KCNB1 at the plasma membrane (PubMed:12060745, PubMed:19074135). Remains intracellular in the absence of KCNB1 (PubMed:12060745).

Diseases

Hypertensive Disease
Adenocarcinoma
Essential Hypertension
Malignant Squamous Cell Neoplasm
Lung Neoplasms
Malignant Paraganglionic Neoplasm
Benign Prostatic Hypertrophy
Malignant Neoplasm Of Lung
Carcinoma

Malignant Neoplasms
Hypertrophy
Neoplasms
Pulmonary Hypertension

Pathways

Localization
Methylation
Dna Hypermethylation
Dna Methylation

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCNG3

References

PMID: 11852086 by Sano Y., et al. Molecular cloning and characterization of Kv6.3, a novel modulatory subunit for voltage-gated K(+) channel Kv2.1.

PMID: 12060745 by Ottschytsch N., et al. Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome.