BRAT1 Antibodies

AND BRAT1 ELISA kits, BRAT1 Proteins

Many biological assays use antibodies to detect BRAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BRAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BRAT1 antibodies...

We validate the specificity of these antibodies to BRAT1 by testing them on tissues known to express BRAT1 positively and negatively. Browse below to find the BRAT1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BRAT1 Infographic by Boster Bio

All BRAT1 Products

Product

Figures

Specificity

Applications

Price

BAAT1 (BRAT1) (NM_152743) Human Recombinant Protein

$1249
Cat # PROTQ6PJG6
20 µg

Anti-BRAT1 Rabbit Monoclonal Antibody

Human

Flow Cytometry, IP, IF, ICC, WB

$370
Cat # M06265
100 μl/vial

BAAT1 (BRAT1) (NM_152743) Human Over-expression Lysate

Human

$628
Cat # LS221927
100 µg

BRAT1 Overview

Facts about BRCA1-associated ATM activator 1.

BRAT1 3D structure. Source: alphafold

BRCA1-associated ATM activator 1 (BRAT1)

Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress (PubMed:16452482, PubMed:22977523). Plays a role in regulating mitochondrial function and cell proliferation (PubMed:25070371).

Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors (PubMed:25657994). .

Gene Information

Human
Gene Name:	BRAT1
Uniprot:	Q6PJG6
Entrez:	221927

Family

Belongs to:

No superfamily

Alternative Names

BAAT1; BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1; C7orf27; chromosome 7 open reading frame 27; HEAT repeat-containing protein C7orf27; MGC22916

Molecular Weight

Mass (kDA):
88.119 kDA

Genomic Context


Human

Location:	7p22.3
Sequence:	7; NC_000007.14 (2537810..2555753, complement)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Nucleus. Cytoplasm. Present at double strand breaks (DSBs)following ionizing radiation treatment. The ubiquitinated form localizes in the nucleus in a NDFIP1-dependent manner.