JAM2 Antibodies

AND JAM2 ELISA kits, JAM2 Proteins

Many biological assays use antibodies to detect JAM2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with JAM2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop JAM2 antibodies...

We validate the specificity of these antibodies to JAM2 by testing them on tissues known to express JAM2 positively and negatively. Browse below to find the JAM2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: OVOL2

JAM2 Infographic by Boster Bio

All JAM2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human JAM-B/JAM2 ELISA Kit PicoKine®

8 Q&As

Human

ELISA

$499
Cat # EK1842
96 wells/kit, with removable strips.

Anti-Junctional adhesion molecule B JAM2 Antibody

Human, Mouse, Rat

$405
Cat # A04298
100ul

Anti-JAM-B JAM2 Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A04298-1
100ul

Human JAM-B/VE-JAM Recombinant Protein

SDS-PAGE

$250
Cat # PROTP57087
Starting from 10ug

Junctional Adhesion Molecule 2 (JAM2) (NM_021219) Human Over-expression Lysate

Human

$628
Cat # LS058494
100 µg

JAM2 Overview

Facts about Junctional adhesion molecule B.

JAM2 3D structure. Source: alphafold

Junctional adhesion molecule B (JAM2)

May play a role in the processes of lymphocyte homing to secondary lymphoid organs. .

Gene Information

Human
Gene Name:	JAM2
Uniprot:	P57087
Entrez:	58494

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

C21orf43; CD322 antigen; CD322; JAM2; JAMB; JAM-B; JAM-BJAM-IT/VE-JAM; junctional adhesion molecule 2JAM-2; junctional adhesion molecule B; PRO245; Vascular endothelial junction-associated molecule; VE-JAM; VE-JAMVEJAMCD322

Molecular Weight

Mass (kDA):
33.207 kDA

Genomic Context


Human

Location:	21q21.3
Sequence:	21; NC_000021.9 (25607550..25717562)

Tissue Specificity

Highest expression in the heart, placenta, lung, foreskin and lymph node. Prominently expressed on high endothelial venules, also present on the endothelia of other vessels. Localized to the intercellular boundaries of high endothelial cells.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Cell junction. Cell junction, tight junction. Localized at tight junctions of both epithelial and endothelial cells (By similarity). Specifically localized within the somatodendritic compartment of neurons and excluded from the axon (By similarity).

Diseases

Tissue Adhesions
Neoplasms
Malignant Neoplasms
Inflammation
Tumor Angiogenesis
Extravasation
Carcinoma
Auricular Swelling
Pathologic Neovascularization
Malignant Paraganglionic Neoplasm
Edema
Sclerosis
Adenoma

Neoplasm Metastasis
Dementia
Glioma
Down Syndrome
Diffuse Scleroderma
Mouth Neoplasms
Gastric Adenocarcinoma

Interacting Proteins

JAM3

Pathways

Cell Adhesion
Localization
Angiogenesis
Immune Response
Lymphangiogenesis
Transport
Diapedesis
Cell Proliferation
Cell Migration
Dna Methylation
Glycosylation
Platelet Activation
Hypersensitivity

Leukocyte Differentiation
Establishment Of Epithelial Cell Polarity
Methylation
Regeneration
Sensitization
Cell Cycle
Transdifferentiation

PTMs

Phosphorylation
Biotinylation

Glycosylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/JAM2

References

PMID: 10779521 by Palmeri D., et al. Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells.

PMID: 10945976 by Cunningham S.A., et al. A novel protein with homology to the junctional adhesion molecule: Characterization of leukocyte interactions.