INTS11 Antibodies

AND INTS11 ELISA kits, INTS11 Proteins

Many biological assays use antibodies to detect INTS11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with INTS11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop INTS11 antibodies...

We validate the specificity of these antibodies to INTS11 by testing them on tissues known to express INTS11 positively and negatively. Browse below to find the INTS11 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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INTS11 Infographic by Boster Bio

All INTS11 Products

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Specificity

Applications

Price

Anti-CPSF3L INTS11 Antibody

Human, Mouse, Rat

IF, WB

$405
Cat # A32417
100ul

INT11 (CPSF3L) (NM_017871) Human Over-expression Lysate

Human

$628
Cat # LS054973
100 µg

INTS11 Overview

Facts about Integrator complex subunit 11.

INTS11 3D structure. Source: alphafold

Integrator complex subunit 11 (INTS11)

Catalytic component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.

Mediates the snRNAs 3' cleavage. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, likely as component of the INT complex (PubMed:23904267).

Gene Information

Human
Gene Name:	INTS11
Uniprot:	Q5TA45
Entrez:	54973

Family

Belongs to:

metallo-beta-lactamase superfamily

Alternative Names

Integrator complex subunit 11

Molecular Weight

Mass (kDA):
67.663 kDA

Genomic Context


Human

Location:	1p36.33
Sequence:	1; NC_000001.11 (1311585..1324687, complement)

Subcellular Localizations

Nucleus. Cytoplasm.

Interacting Proteins

INTS9

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/INTS11

References

PMID: 16239144 by Baillat D., et al. Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

PMID: 15684398 by Dominski Z., et al. A CPSF-73 homologue is required for cell cycle progression but not cell growth and interacts with a protein having features of CPSF- 100.