THG1L Antibodies

AND THG1L ELISA kits, THG1L Proteins

Many biological assays use antibodies to detect THG1L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with THG1L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop THG1L antibodies...

We validate the specificity of these antibodies to THG1L by testing them on tissues known to express THG1L positively and negatively. Browse below to find the THG1L antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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THG1L Infographic by Boster Bio

All THG1L Products

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Specificity

Applications

Price

THG1L (NM_017872) Human Recombinant Protein

$813
Cat # PROTQ9NWX6
20 µg

THG1L (NM_017872) Human Over-expression Lysate

Human

$628
Cat # LS054974
100 µg

THG1L Overview

Facts about Probable tRNA(His) guanylyltransferase.

THG1L 3D structure. Source: alphafold

Probable tRNA(His) guanylyltransferase (THG1L)

Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
This step is essential for appropriate recognition of the tRNA and for the fidelity of protein synthesis.

Gene Information

Human
Gene Name:	THG1L
Uniprot:	Q9NWX6
Entrez:	54974

Family

Belongs to:

tRNA(His) guanylyltransferase family

Alternative Names

EC 2.7.7; EC 2.7.7.6; FLJ11601; FLJ20546; ICF45EC 2.7.7.-; Interphase cytoplasmic foci protein 45; probable tRNA(His) guanylyltransferase; tRNA-histidine guanylyltransferase 1-like (S. cerevisiae); tRNA-histidine guanylyltransferase

Molecular Weight

Mass (kDA):
34.831 kDA

Genomic Context


Human

Location:	5q33.3
Sequence:	5; NC_000005.10 (157731420..157741449)

Tissue Specificity

Expressed in many tissues.

Subcellular Localizations

Cytoplasm. Found near the nuclear membrane.

Interacting Proteins

SDCBP
TERF1

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/THG1L

References

PMID: 15459185 by Guo D., et al. Identification and characterization of a novel cytoplasm protein ICF45 that is involved in cell cycle regulation.

PMID: 21059936 by Hyde S.J., et al. tRNA(His) guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'- 3' DNA polymerases.