INTS10 Antibodies

AND INTS10 ELISA kits, INTS10 Proteins

Many biological assays use antibodies to detect INTS10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with INTS10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop INTS10 antibodies...

We validate the specificity of these antibodies to INTS10 by testing them on tissues known to express INTS10 positively and negatively. Browse below to find the INTS10 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: KLHL11

INTS10 Infographic by Boster Bio

All INTS10 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Integrator complex subunit 10 INTS10 Antibody

Human, Mouse

IF, ICC, WB

$405
Cat # A12735
100ul

INTS10 Overview

Facts about Integrator complex subunit 10.

INTS10 3D structure. Source: alphafold

Integrator complex subunit 10 (INTS10)

Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable).

May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex (PubMed:23904267). .

Gene Information

Human
Gene Name:	INTS10
Uniprot:	Q9NVR2
Entrez:	55174

Family

Belongs to:

Integrator subunit 10 family

Alternative Names

C8orf35; INT10; integrator complex subunit 10

Molecular Weight

Mass (kDA):
82.236 kDA

Genomic Context


Human

Location:	8p21.3
Sequence:	8; NC_000008.11 (19817149..19852083)

Subcellular Localizations

Nucleus.

Diseases

Cell Transformation, Neoplastic
Leukemia
Chromosomal Translocation
Malignant Disease (disorder)
Malignant Paraganglionic Neoplasm
L1 Acute Lymphoblastic Leukemia

Acute Lymphocytic Leukemia

Pathways

Spermatogenesis

PTMs

Isopeptide bond

Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/INTS10

References

PMID: 16239144 by Baillat D., et al. Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

PMID: 23904267 by Jodoin J.N., et al. Nuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the integrator complex.