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- Table of Contents
Facts about Protein IWS1 homolog.
The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure appropriate mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a touch chromatin markers of active transcription. .
Human | |
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Gene Name: | IWS1 |
Uniprot: | Q96ST2 |
Entrez: | 55677 |
Belongs to: |
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IWS1 family |
DKFZp761G0123; FLJ14655; interacts with Spt6; IWS1 homolog (S. cerevisiae); protein IWS1 homolog
Mass (kDA):
91.955 kDA
Human | |
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Location: | 2q14.3 |
Sequence: | 2; NC_000002.12 (127480807..127526886, complement) |
Nucleus.
PMID: 15302935 by Beausoleil S.A., et al. Large-scale characterization of HeLa cell nuclear phosphoproteins.
PMID: 17184735 by Liu Z., et al. A putative transcriptional elongation factor hIws1 is essential for mammalian cell proliferation.