Interferon regulatory factor 2-binding protein 2 (Irf2bp2)

Acts as a transcriptional corepressor in a IRF2- dependent fashion, this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters.

Acts as a coactivator of VEGFA expression in cardiac and skeletal muscle (By similarity). .