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IRAK2 Antibodies
AND IRAK2 ELISA kits, IRAK2 Proteins
Many biological assays use antibodies to detect IRAK2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IRAK2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IRAK2 antibodies...
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IRAK2 Infographic by Boster Bio
All IRAK2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01559
100 μg/vial
Cat # A01559
100 μg/vial
IRAK2 Overview
Facts about Interleukin-1 receptor-associated kinase-like 2.
Interleukin-1 receptor-associated kinase-like 2 (IRAK2)
Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. .
Gene Information
| Human | |
|---|---|
| Gene Name: | IRAK2 |
| Uniprot: | O43187 |
| Entrez: | 3656 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
interleukin-1 receptor associated kinase-2; interleukin-1 receptor-associated kinase 2; interleukin-1 receptor-associated kinase-like 2; IRAK2; IRAK-2; MGC150550
Molecular Weight
Mass (kDA):
69.433 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p25.3 |
| Sequence: | 3; NC_000003.12 (10164919..10243745) |
Tissue Specificity
Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.
Diseases
- Inflammation
- Innate Immune Response
- Malignant Neoplasms
- Neoplasms
- Vaccinia
- Inflammatory Response
- Infective Disorder
- Carcinoma
- Bacterial Infections
- Liver Carcinoma
- Asthma
- Cell Invasion
Interacting Proteins
- ARAF
- IRAK4
- Sarm1
- STT3A
- TARDBP
- TIRAP
- TOLLIP
- TRAF6
- ZC3H12A
Pathways
- Immune Response
- Innate Immune Response
- Secretion
- Chemokine Production
- Inflammatory Response
- Cytokine Production
- Translation
- Cell Cycle
- Cell Death
- Protein Phosphorylation
- Toll-like Receptor Signaling Pathway
- Induction Of Apoptosis
PTMs
- Phosphorylation
Research Areas
- Immunology
- Innate Immunity
- Protein Kinase
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IRAK2
bosterbio.com/bosterbio-gene-info-cards/IRAK2
References
PMID: 9374458 by Muzio M., et al. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling.
PMID: 10383454 by Wesche H., et al. IRAK-M is a novel member of the Pelle/interleukin-1 receptor- associated kinase (IRAK) family.