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- Table of Contents
Facts about Insulinoma-associated protein 2.
Mouse | |
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Gene Name: | Insm2 |
Uniprot: | Q9JMC2 |
Entrez: | 56856 |
Belongs to: |
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No superfamily |
insulinoma-associated 2; Nbla106; zinc finger protein IA-6
Mass (kDA):
52.225 kDA
Mouse | |
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Location: | 12|12 C1 |
Sequence: | 12; |
Expressed in spleen, stomach, liver, kidney and testis. In the pancreas, expressed in islet cells, including insulin-producing beta-cells, but not in acinar cells (at protein level). In the brain, expressed in the neuronal cells of the cerebral cortex, the Purkinje cells of the cerebellum and the hippocampal region including CA1 and CA3 (at protein level).
PMID: 11221845 by Tateno M., et al. Identification of a novel member of the snail/Gfi-1 repressor family, mlt 1, which is methylated and silenced in liver tumors of SV40 T antigen transgenic mice.
PMID: 21343251 by Cai T., et al. Expression of insulinoma-associated 2 (INSM2) in pancreatic islet cells is regulated by the transcription factors Ngn3 and NeuroD1.