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- Table of Contents
Facts about Interleukin-10 receptor subunit beta.
The ligand/receptor complex stimulate the activation of this JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. .
Human | |
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Gene Name: | IL10RB |
Uniprot: | Q08334 |
Entrez: | 3588 |
Belongs to: |
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type II cytokine receptor family |
CDw210b antigen; CDw210b; CRF2-4IL-10R subunit 2; CRFB4; CRFB4human transmembrane receptor protein; cytokine receptor10CDW210B; D21S58; D21S66; IBD25; IL-10 R beta; IL-10 receptor subunit beta; IL10R beta; IL-10R2; IL-10R2IL-10R subunit beta; IL10RB; IL-10Rb; interleukin 10 receptor, beta; Interleukin-10 receptor subunit 2; interleukin-10 receptor subunit beta; member 4
Mass (kDA):
36.995 kDA
Human | |
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Location: | 21q22.11 |
Sequence: | 21; NC_000021.9 (33266367..33297221) |
Membrane; Single-pass type I membrane protein.
PMID: 8314576 by Lutfalla G., et al. A new member of the cytokine receptor gene family maps on chromosome 21 at less than 35 kb from IFNAR.
PMID: 7563119 by Lutfalla G., et al. Structure of the human CRFB4 gene: comparison with its IFNAR neighbor.