IL11RA Antibodies

AND IL11RA ELISA kits, IL11RA Proteins

Many biological assays use antibodies to detect IL11RA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IL11RA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IL11RA antibodies...

We validate the specificity of these antibodies to IL11RA by testing them on tissues known to express IL11RA positively and negatively. Browse below to find the IL11RA antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: IL12RB2

IL11RA Infographic by Boster Bio

All IL11RA Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-IL11RA Antibody

4 Q&As

Human

$360
Cat # A06426
100 µl

Anti-IL11RA Antibody

Human, Mouse, Rat

$405
Cat # A06426-1
100ul

Anti-IL11RA Rabbit Monoclonal Antibody

Human, Mouse

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M06426
100 μl/vial

IL11RA (NM_004512) Human Over-expression Lysate

Human

$628
Cat # LS003590
100 µg

IL11RA Overview

Facts about Interleukin-11 receptor subunit alpha.

IL11RA 3D structure. Source: alphafold

Interleukin-11 receptor subunit alpha (IL11RA)

Receptor for interleukin-11.
The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission.

The IL11/IL11RA/IL6ST complex might be involved in the control of proliferation and/or distinction of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth.

Gene Information

Human
Gene Name:	IL11RA
Uniprot:	Q14626
Entrez:	3590

Family

Belongs to:

type I cytokine receptor family

Alternative Names

AI314697; GP130; IL-11 R alpha; IL11R alpha; IL11RA; IL-11Ra; Il11ra2; NR1

Molecular Weight

Mass (kDA):
45.222 kDA

Genomic Context


Human

Location:	9p13.3
Sequence:	9; NC_000009.12 (34652185..34661902)

Tissue Specificity

Expressed in a number of cell lines, including the myelogenous leukemia cell line K-562, the megakaryocytic leukemia cell line M-07e, the erythroleukemia cell line TF-1, and the osteosarcoma cell lines, MG-63 and SaOS-2. Also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increased in prostate carcinoma.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Leukemia
Endometrial Polyp
Malignant Neoplasms
Neoplasms
Carcinoma
Infertility
Malignant Paraganglionic Neoplasm
Cell Invasion
Plasmacytoma
Liver Carcinoma
Neoplasm Metastasis
Osteosarcoma
Tissue Adhesions

Female Infertility
Malignant Neoplasm Of Breast
Craniosynostosis
Myeloid Leukemia
Hypoplasia
Inflammation
Multiple Myeloma

Pathways

Decidualization
Cell Proliferation
Embryo Implantation
Secretion
Cell Adhesion
Localization
Cell Growth
Immune Response
Cell Differentiation
Glycosylation
Cytokine Production
Cell Death
Protein Phosphorylation

Embryonic Skeletal System Development
Osteoclast Development
Programmed Cell Death
Developmental Process
Osteoblast Differentiation
Organic Acid Metabolic Process
Neurogenesis

PTMs

Phosphorylation

Glycosylation

Demethylation

Research Areas

Cytokine Research
Immunology
Innate Immunity

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL11RA

References

PMID: 7670098 by Cherel M., et al. Molecular cloning of two isoforms of a receptor for the human hematopoietic cytokine interleukin-11.

PMID: 8808281 by Van Leuven F., et al. Molecular cloning and characterization of the human interleukin-11 receptor alpha-chain gene, IL11RA, located on chromosome 9p13.