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- Table of Contents
Facts about Interleukin-10 receptor subunit alpha.
Receptor for IL10; binds IL10 Using a high affinity.
.Human | |
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Gene Name: | IL10RA |
Uniprot: | Q13651 |
Entrez: | 3587 |
Belongs to: |
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type II cytokine receptor family |
CD210 antigen; CDw210a; HIL-10R; IBD28; IL-10 R alpha; IL-10 receptor subunit alpha; IL10R alpha; IL-10R subunit 1; IL-10R1; IL10RA; IL-10Ra; IL10RIL-10R subunit alpha; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; Interleukin-10 receptor subunit 1; interleukin-10 receptor subunit alpha
Mass (kDA):
63.003 kDA
Human | |
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Location: | 11q23.3 |
Sequence: | 11; NC_000011.10 (117986394..118003037) |
Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.
Cell membrane; Single-pass type I membrane protein. Cytoplasm.
PMID: 8120391 by Liu Y., et al. Expression cloning and characterization of a human IL-10 receptor.
PMID: 12133952 by Usacheva A., et al. Two distinct domains within the N-terminal region of Janus kinase 1 interact with cytokine receptors.