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- Table of Contents
Facts about Immunoglobulin lambda-like polypeptide 1.
Critical for B-cell development.
.Human | |
---|---|
Gene Name: | IGLL1 |
Uniprot: | P15814 |
Entrez: | 3543 |
Belongs to: |
---|
No superfamily |
14.1; AGM2; CD179 antigen-like family member B; CD179b antigen; CD179b; Ig lambda-5; IGL1; IGL5; IGL5CD179B; IGLJ14.1; IGLL; IGLL1; IGO; IGVPB; immunoglobulin lambda-like polypeptide 1; immunoglobulin omega polypeptide chain; Immunoglobulin omega polypeptide; immunoglobulin-related 14.1 protein; Immunoglobulin-related protein 14.1; Lambda5; Pre-B lymphocyte-specific protein-2; VPREB2
Mass (kDA):
22.963 kDA
Human | |
---|---|
Location: | 22q11.23 |
Sequence: | 22; NC_000022.11 (23573125..23580290, complement) |
Expressed only in pre-B-cells and a special B- cell line (which is surface Ig negative).
Secreted.
PMID: 2501791 by Hollis G.F., et al. Immunoglobulin lambda light-chain-related genes 14.1 and 16.1 are expressed in pre-B cells and may encode the human immunoglobulin omega light-chain protein.
PMID: 1703205 by Evans R.J., et al. Genomic structure of the human Ig lambda 1 gene suggests that it may be expressed as an Ig lambda 14.1-like protein or as a canonical B cell Ig lambda light chain: implications for Ig lambda gene evolution.