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- Table of Contents
Facts about Immunoglobulin kappa variable 1D-16.
In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).
Human | |
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Gene Name: | IGKV1D-16 |
Uniprot: | P01601 |
Entrez: | 28901 |
Belongs to: |
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No superfamily |
Immunoglobulin kappa variable 1D-16
Mass (kDA):
12.73 kDA
Human | |
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Location: | 2p11.2 |
Sequence: | 2; NC_000002.12 (90100263..90100738) |
Secreted. Cell membrane.
PMID: 6779204 by Bentley D.L., et al. Human immunoglobulin variable region genes -- DNA sequences of two V kappa genes and a pseudogene.
PMID: 6402305 by Bentley D.L., et al. Evolution of immunoglobulin V genes: evidence indicating that recently duplicated human V kappa sequences have diverged by gene conversion.