IGF2BP3 Antibodies

AND IGF2BP3 ELISA kits, IGF2BP3 Proteins

Many biological assays use antibodies to detect IGF2BP3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IGF2BP3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IGF2BP3 antibodies...

We validate the specificity of these antibodies to IGF2BP3 by testing them on tissues known to express IGF2BP3 positively and negatively. Browse below to find the IGF2BP3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IGF2BP3 Infographic by Boster Bio

All IGF2BP3 Products

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Product

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Specificity

Applications

Price

Anti-IMP3 IGF2BP3 Monoclonal Antibody

3 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, IF, ICC, WB

$370
Cat # M02362-1
100 μl

Anti-IMP3 (IGF2BP3) Mouse Monoclonal Antibody [Clone ID: OTI4H5]

Human, Mouse, Rat

IHC, WB

$523
Cat # M02362
100 µl

Anti-IMP3/IGF2BP3 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A02362-1
100 μg/vial

IMP3 (IGF2BP3) (NM_006547) Human Over-expression Lysate

Human

$628
Cat # LS010643
100 µg

IGF2BP3 Overview

Facts about Insulin-like growth factor 2 mRNA-binding protein 3.

IGF2BP3 3D structure. Source: alphafold

Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)

RNA-binding factor that may recruit target transcripts into cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage.

It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease strikes or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells.

Gene Information

Human
Gene Name:	IGF2BP3
Uniprot:	O00425
Entrez:	10643

Family

Belongs to:

RRM IMP/VICKZ family

Alternative Names

CT98; hKOC; IGF II mRNA binding protein 3; IGF2 mRNA-binding protein 3; IGF-II mRNA-binding protein 3; IMP-3KH domain-containing protein overexpressed in cancer; IMP3VICKZ family member 3; insulin-like growth factor 2 mRNA binding protein 3; insulin-like growth factor 2 mRNA-binding protein 3; KH domain containing protein overexpressed in cancer; KOC1DKFZp686F1078; VICKZ3cancer/testis antigen 98

Molecular Weight

Mass (kDA):
63.705 kDA

Genomic Context


Human

Location:	7p15.3
Sequence:	7; NC_000007.14 (23310209..23470674, complement)

Tissue Specificity

Expressed in fetal liver, fetal lung, fetal kidney, fetal thymus, fetal placenta, fetal follicles of ovary and gonocytes of testis, growing oocytes, spermatogonia and semen (at protein level). Expressed in cervix adenocarcinoma, in testicular, pancreatic and renal-cell carcinomas (at protein level). Expressed ubiquitously during fetal development at 8 and 14 weeks of gestation. Expressed in ovary, testis, brain, placenta, pancreatic cancer tissues and pancreatic cancer cell lines.

Subcellular Localizations

Nucleus. Cytoplasm. Found in lamellipodia of the leading edge, in the perinuclear region, and beneath the plasma membrane. The subcytoplasmic localization is cell specific and regulated by cell contact and growth. Localized at the connecting piece and the tail of the spermatozoa. Colocalized with CD44 mRNA in RNP granules. In response to cellular stress, such as oxidative stress, recruited to stress granules.