IGF2BP2 Antibodies

AND IGF2BP2 ELISA kits, IGF2BP2 Proteins

Many biological assays use antibodies to detect IGF2BP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IGF2BP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IGF2BP2 antibodies...

We validate the specificity of these antibodies to IGF2BP2 by testing them on tissues known to express IGF2BP2 positively and negatively. Browse below to find the IGF2BP2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IGF2BP2 Infographic by Boster Bio

All IGF2BP2 Products

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Product

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Specificity

Applications

Price

Anti-IGF2BP2 Mouse Monoclonal Antibody [Clone ID: OTI3F9]

Dog, Human, Monkey, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M02010
100 µl

Anti-IMP2 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M02010-1
100 μl/vial

Anti-IGF2BP2 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # M02010-2
100 μl/vial

IGF2BP2 (NM_006548) Human Over-expression Lysate

Human

$628
Cat # LS010644
100 µg

IGF2BP2 Overview

Facts about Insulin-like growth factor 2 mRNA-binding protein 2.

IGF2BP2 3D structure. Source: alphafold

Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)

RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage.

Additionally, it modulates the rate and location where target transcripts encounter the translational apparatus and shields them from endonuclease strikes or microRNA-mediated degradation (By similarity). Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.

Gene Information

Human
Gene Name:	IGF2BP2
Uniprot:	Q9Y6M1
Entrez:	10644

Family

Belongs to:

RRM IMP/VICKZ family

Alternative Names

Hepatocellular carcinoma autoantigen p62; IF2B2; IGF2BP2; IGF-II mRNA-binding protein 2; IMP2; IMP-2IGF2 mRNA-binding protein 2; IMP2VICKZ family member 2; insulin-like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA-binding protein 2; p62; VICKZ2

Molecular Weight

Mass (kDA):
66.121 kDA

Genomic Context


Human

Location:	3q27.2
Sequence:	3; NC_000003.12 (185643130..185825046, complement)

Tissue Specificity

Expressed in oocytes, granulosa cells of small and growing follicles, Leydig cells, spermatogonia and semen (at protein level). Expressed in testicular cancer (at protein level). Expressed weakly in heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis and pancreas. Detected in fetal liver, fetal ovary, gonocytes and interstitial cells of the testis.

Subcellular Localizations

Nucleus. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Localizes at the connecting piece and the tail of the spermatozoa. In response to cellular stress, such as oxidative stress, recruited to stress granules.