IFNLR1 Antibodies

AND IFNLR1 ELISA kits, IFNLR1 Proteins

Many biological assays use antibodies to detect IFNLR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IFNLR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IFNLR1 antibodies...

We validate the specificity of these antibodies to IFNLR1 by testing them on tissues known to express IFNLR1 positively and negatively. Browse below to find the IFNLR1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IFNLR1 Infographic by Boster Bio

All IFNLR1 Products

Product

Figures

Specificity

Applications

Price

Anti-IL-28 alpha IFNLR1 Antibody

Human

ELISA, WB

$380
Cat # A05986
100ul

Anti-IL28RA Antibody (Center)

Human

$298
Cat # M05986
80 µl

Anti-IL28 Receptor alpha (IFNLR1) Mouse Monoclonal Antibody [Clone ID: OTI3F5]

Human

IHC, WB

$523
Cat # M05986-1
100 µl

IL28 Receptor alpha (IFNLR1) (NM_173064) Human Over-expression Lysate

Human

$960
Cat # LS163702
100 µg

IFNLR1 Overview

Facts about Interferon lambda receptor 1.

IFNLR1 3D structure. Source: alphafold

Interferon lambda receptor 1 (IFNLR1)

The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.

Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts.

Gene Information

Human
Gene Name:	IFNLR1
Uniprot:	Q8IU57
Entrez:	163702

Family

Belongs to:

type II cytokine receptor family

Alternative Names

class II cytokine receptor CRF2/12; CRF2/12; CRF2-12; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; IFN-lambda R1; IFN-lambda receptor 1; IFN-lambda-R1; IFNLR; IFNLR1; IL-28 R alpha; IL-28 receptor subunit alpha; IL28R alpha; IL-28R1; IL28RA; IL-28Ra; IL-28R-alpha; Interferon lambda receptor 1; interferon lambda, receptor 1; interleukin 28 receptor A; interleukin 28 receptor, alpha (interferon, lambda receptor); interleukin 28 receptor, alpha; interleukin or cytokine receptor 2; interleukin-28 receptor subunit alpha; LICR2; Likely interleukin or cytokine receptor

Molecular Weight

Mass (kDA):
57.653 kDA

Genomic Context


Human

Location:	1p36.11
Sequence:	1; NC_000001.11 (24154156..24187295, complement)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IFNLR1

References

PMID: 12521379 by Dumoutier L., et al. Cloning of a new type II cytokine receptor activating signal transducer and activator of transcription (STAT)1, STAT2 and STAT3.

PMID: 12469119 by Sheppard P., et al. IL-28, IL-29 and their class II cytokine receptor IL-28R.