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- Table of Contents
Facts about Radiation-inducible immediate-early gene IEX-1.
As a member of the NUPR1/RELB/IER3 survival pathway, can offer pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine therapy. .
Human | |
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Gene Name: | IER3 |
Uniprot: | P46695 |
Entrez: | 8870 |
Belongs to: |
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IER3 family |
DIF-2; DIF2GLY96; Differentiation-dependent gene 2 protein; expressed in pancreatic carcinoma; gly96, mouse, homolog of; IEX-1; IEX1death protein; IEX-1L; Immediate early protein GLY96; Immediate early response 3 protein; immediate early response 3; immediately early gene X-1; PRG1PACAP-responsive gene 1 protein; Protein DIF-2; Protein PRG1; radiation-inducible immediate-early gene IEX-1
Mass (kDA):
16.903 kDA
Human | |
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Location: | 6p21.33 |
Sequence: | 6; NC_000006.12 (30743199..30744547, complement) |
Membrane; Single-pass type II membrane protein.
PMID: 8603392 by Kondratyev A.D., et al. Identification and characterization of a radiation-inducible glycosylated human early-response gene.
PMID: 8653710 by Schaefer H., et al. PRG1: a novel early-response gene transcriptionally induced by pituitary adenylate cyclase activating polypeptide in a pancreatic carcinoma cell line.