ID4 Antibodies

AND ID4 ELISA kits, ID4 Proteins

Many biological assays use antibodies to detect ID4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ID4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ID4 antibodies...

We validate the specificity of these antibodies to ID4 by testing them on tissues known to express ID4 positively and negatively. Browse below to find the ID4 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ID4 Infographic by Boster Bio

All ID4 Products

Product

Figures

Specificity

Applications

Price

Anti-ID4 Antibody

2 Citations 5 Q&As

Human, Mouse, Rat

$360
Cat # A03975
100 µl

ID4 Colorimetric Cell-Based ELISA

Human, Mouse, Rat

ELISA

$480
Cat # EKC1725
1 kit, containing one 96-well plate and all necessary reagents

Anti-Id4 (S5) Antibody

Human, Mouse, Rat

IHC

$405
Cat # A03975S5
100ul

Anti-Id4 Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A03975-1
100ul

Anti-ID4 Mouse Monoclonal Antibody [Clone ID: OTI2G10]

Human, Mouse, Rat

$523
Cat # M03975
100 µl

ID4 (NM_001546) Human Over-expression Lysate

Human

$628
Cat # LS003400
100 µg

ID4 Overview

Facts about DNA-binding protein inhibitor ID-4.

ID4 3D structure. Source: alphafold

DNA-binding protein inhibitor ID-4 (ID4)

Transcriptional regulator (lacking a basic DNA binding domain) which simplifies the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, such as cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation (By similarity).

. .

Gene Information

Human
Gene Name:	ID4
Uniprot:	P47928
Entrez:	3400

Family

Belongs to:

No superfamily

Alternative Names

bHLHb27BHLHB27; Class B basic helix-loop-helix protein 27; DNA-binding protein inhibitor ID-4; IDB4; Inhibitor of DNA binding 4; inhibitor of DNA binding 4, dominant negative helix-loop-helix protein

Molecular Weight

Mass (kDA):
16.622 kDA

Genomic Context


Human

Location:	6p22.3
Sequence:	6; NC_000006.12 (19837370..19842197)

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Malignant Neoplasms
Lymphohistiocytosis, Hemophagocytic
Cell Transformation, Neoplastic
Leukemia
Malignant Neoplasm Of Breast
Mammary Neoplasms
Malignant Paraganglionic Neoplasm
Nervousness
Neoplasm Metastasis
Leukemia, Myelocytic, Acute
Carcinogenesis
Myeloid Leukemia

Carcinoma
Acute Lymphocytic Leukemia
Hyperplasia
Adenocarcinoma
Lymphoma
Tumor Angiogenesis
Prostatic Neoplasms

Interacting Proteins

NCK1

Pathways

Methylation
Cell Proliferation
Cell Cycle
Cell Differentiation
Dna Methylation
Gene Silencing
Cell Growth
Pathogenesis
Localization
Neurogenesis
Oligodendrocyte Differentiation
Spermatogenesis
Angiogenesis

Myelination
Oligodendrocyte Development
Demethylation
Senescence
Osteoblast Differentiation
Mammary Gland Development
Gland Development

PTMs

Methylation
Demethylation
Phosphorylation
Reduction

Cleavage
Acetylation
Ubiquitination
Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ID4

References

PMID: 9872455 by Rigolet M., et al. cDNA cloning, tissue distribution and chromosomal localization of the human ID4 gene.

PMID: 7665172 by Pagliuca A., et al. Molecular cloning of ID4, a novel dominant negative helix-loop-helix human gene on chromosome 6p21.3-p22.

2 Publications of Boster ID4 Antibodies & ELISA Kits

PubMed ID: 10.24272/j.issn.2095-8137.2020.186, Dmrt1 regulates the immune response by repressing the TLR4 signaling pathway in ...
PubMed ID: 10.1002/jcp.29954, PAX7 promotes CD49f‐positive dairy goat spermatogonial stem cells self‐renew...

*More publications can be found for each product on its corresponding product page