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- Table of Contents
Facts about HIV Tat-specific factor 1.
In case of infection by HIV-1, it's up-regulated from the HIV-1 proteins NEF and gp120, functions as a cofactor necessary for the Tat-enhanced transcription of the virus. .
Human | |
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Gene Name: | HTATSF1 |
Uniprot: | O43719 |
Entrez: | 27336 |
Belongs to: |
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HTATSF1 family |
cofactor required for Tat activation of HIV-1 transcription; dJ196E23.2; HIV TAT specific factor 1; HIV Tat-specific factor 1; HIV-1 Tat specific factor 1; TAT-SF1
Mass (kDA):
85.853 kDA
Human | |
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Location: | Xq26.3 |
Sequence: | X; NC_000023.11 (136497079..136512346) |
Widely expressed.
Nucleus.
PMID: 8849451 by Zhou Q., et al. Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat.
PMID: 9649438 by Zhou Q., et al. Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages.