Histone H2A type 2-A Antibodies

AND Hist2h2aa3 ELISA kits, Histone H2A type 2-A Proteins

Many biological assays use antibodies to detect Histone H2A type 2-A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H2A type 2-A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H2A type 2-A antibodies...

We validate the specificity of these antibodies to Histone H2A type 2-A by testing them on tissues known to express Hist2h2aa3 positively and negatively. Browse below to find the Hist2h2aa3 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Hist2h2aa3 Infographic by Boster Bio

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Hist2h2aa3 Overview

Facts about Histone H2A type 2-A.

Histone H2A type 2-A (Hist2h2aa3)

Core part of nucleosome. Nucleosomes compact and wrap DNA into chromatin, restricting DNA access to the cellular machineries which require DNA as a template.

Histones thus play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).

Gene Information

Rat
Gene Name:	Hist2h2aa3
Uniprot:	P0CC09
Entrez:	365877

Family

Belongs to:

histone H2A family

Alternative Names

H2A histone family, member O; H2A.2; H2A/O; H2A/q; H2a-615; H2AFOHistone H2A/o; HIST2H2AAH2A; histone 2, H2aa; histone 2, H2aa3; histone cluster 2, H2aa3; histone H2A type 2-A; Histone H2A.2

Molecular Weight

Mass (kDA):
14.095 kDA

Genomic Context


Rat

Location:	2q34
Sequence:	2;

Diseases

Testicular Neoplasms
Malignant Neoplasms
Malignant Neoplasm Of Testis

PTMs

Acetylation
Citrullination
Hydroxylation

Isopeptide bond
Methylation
Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Hist2h2aa3

References

PMID: 19343714 by Pramod K.S., et al. Mass spectrometry-compatible silver staining of histones resolved on acetic acid-urea-Triton PAGE.

PMID: 21239733 by Khare S.P., et al. Overexpression of histone variant H2A.1 and cellular transformation are related in N-nitrosodiethylamine-induced sequential hepatocarcinogenesis.