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- Table of Contents
Facts about Transcription factor HES-7.
May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May serve as a segmentation clock, which is vital for coordinated somite segmentation.
Mouse | |
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Gene Name: | Hes7 |
Uniprot: | Q8BKT2 |
Entrez: | 84653 |
Belongs to: |
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No superfamily |
bHLH factor Hes7; BHLHB37; bHLHb37transcription factor HES-7; Class B basic helix-loop-helix protein 37; hairy and enhancer of split 7 (Drosophila); Hairy and enhancer of split 7; hHes7; SCDO4
Mass (kDA):
24.89 kDA
Mouse | |
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Location: | 11 B3|11 42.38 cM |
Sequence: | 11; |
PMID: 11260262 by Bessho Y., et al. Hes7: a bHLH-type repressor gene regulated by Notch and expressed in the presomitic mesoderm.
PMID: 15170214 by Hirata H., et al. Instability of Hes7 protein is crucial for the somite segmentation clock.