HYOU1 Antibodies

AND HYOU1 ELISA kits, HYOU1 Proteins

Many biological assays use antibodies to detect HYOU1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HYOU1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HYOU1 antibodies...

We validate the specificity of these antibodies to HYOU1 by testing them on tissues known to express HYOU1 positively and negatively. Browse below to find the HYOU1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HYOU1 Infographic by Boster Bio

All HYOU1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Hypoxia up-regulated protein 1 HYOU1 Antibody

Human, Mouse

IHC, WB

$405
Cat # A04934
100ul

Anti-ORP150 HYOU1 Antibody

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$405
Cat # A04934-1
100ul

Anti-ORP150/HYOU1 Antibody Picoband®

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A04934-2
100 μg/vial

Anti-ORP150 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # M04934-2
100 μl/vial

HYOU1 Overview

Facts about Hypoxia up-regulated protein 1.

HYOU1 3D structure. Source: alphafold

Hypoxia up-regulated protein 1 (HYOU1)

Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding.

Gene Information

Human
Gene Name:	HYOU1
Uniprot:	Q9Y4L1
Entrez:	10525

Family

Belongs to:

heat shock protein 70 family

Alternative Names

150 kDa oxygen-regulated protein; 170 kDa glucose-regulated protein; DKFZp686N08236; FLJ97572; glucose-regulated protein 170; Grp170; GRP-170; HSP12A; HYOU1; hypoxia up-regulated 1; hypoxia up-regulated protein 1; ORP150; ORP-150; ORP150FLJ94899; oxygen regulated protein (150kD)

Molecular Weight

Mass (kDA):
111.335 kDA

Genomic Context


Human

Location:	11q23.3
Sequence:	11; NC_000011.10 (119044187..119057205, complement)

Tissue Specificity

Highly expressed in tissues that contain well- developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers.

Subcellular Localizations

Endoplasmic reticulum lumen.

Diseases

Neoplasms
Malignant Neoplasms
Neoplasm Metastasis
Ataxia
Hypoxia
Neoplasm Invasiveness
Endoplasmic Reticulum Stress
Fibrosis
Malignant Paraganglionic Neoplasm
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Marinesco-sjogren Syndrome
Neurodegenerative Disorders

Cell Invasion
Kidney Fibrosis
Spinocerebellar Degeneration
Metastatic Malignant Neoplasm To The Lymph Node
Diabetic Nephropathy
Malignant Neoplasm Of Breast
Carcinoma

Interacting Proteins

HSPA5

Pathways

Protein Folding
Fertilization
Localization
Translation
Pathogenesis
Transport
Cell Migration
Vesicle Transport
Meiosis Ii
Oocyte Maturation
Chromosome Segregation
Rna Splicing

Phagocytosis
Acrosome Reaction
Dedifferentiation
Angiogenesis
Glycolysis
Meiosis

PTMs

Phosphorylation

Biotinylation

Oxidation

Research Areas

Hypoxia

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HYOU1

References

PMID: 9020069 by Ikeda J., et al. Cloning and expression of cDNA encoding the human 150 kDa oxygen- regulated protein, ORP150.

PMID: 10965054 by Kaneda S., et al. Production of three distinct mRNAs of 150 kDa oxygen-regulated protein (ORP150) by alternative promoters: preferential induction of one species under stress conditions.