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- Table of Contents
Facts about Protein Hook homolog 3.
The FHF complex may function to promote vesicle trafficking and/or mix through the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors like MSR1.
Human | |
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Gene Name: | HOOK3 |
Uniprot: | Q86VS8 |
Entrez: | 84376 |
Belongs to: |
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hook family |
FLJ31058; hHK3; HK3h-hook3; hook homolog 3 (Drosophila); protein Hook homolog 3
Mass (kDA):
83.126 kDA
Human | |
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Location: | 8p11.21 |
Sequence: | 8; NC_000008.11 (42896978..43030535) |
Cytoplasm, cytoskeleton. Golgi apparatus. Enriched at the cis-face of the Golgi complex. Localizes to microtubule asters in prophase (PubMed:11238449). Localizes to the manchette in elongating spermatids (By similarity).
PMID: 11238449 by Walenta J.H., et al. The Golgi-associated hook3 protein is a member of a novel family of microtubule-binding proteins.
PMID: 17237231 by Sano H., et al. The microtubule-binding protein Hook3 interacts with a cytoplasmic domain of scavenger receptor A.