Homer protein homolog 3 Antibodies

AND HOMER3 ELISA kits, Homer protein homolog 3 Proteins

Many biological assays use antibodies to detect Homer protein homolog 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homer protein homolog 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homer protein homolog 3 antibodies...

We validate the specificity of these antibodies to Homer protein homolog 3 by testing them on tissues known to express HOMER3 positively and negatively. Browse below to find the HOMER3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HOMER3 Infographic by Boster Bio

All HOMER3 Products

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Product

Figures

Specificity

Applications

Price

Anti-HOMER3 Antibody Picoband®

5 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # A09145-1
100 μg/vial

Anti-HOMER3 Antibody Picoband® (monoclonal, 9G13)

1 Q&As

Human

Flow Cytometry, WB

$370
Cat # M09145
100 μg/vial

HOMER3 (NM_004838) Human Recombinant Protein

$1062
Cat # PROTQ9NSC5
20 µg

HOMER3 Overview

Facts about Homer protein homolog 3.

HOMER3 3D structure. Source: alphafold

Homer protein homolog 3 (HOMER3)

Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic areas of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3.

By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and might play an important role in maintaining the plasticity at glutamatergic synapses.

Gene Information

Human
Gene Name:	HOMER3
Uniprot:	Q9NSC5
Entrez:	9454

Family

Belongs to:

Homer family

Alternative Names

homer homolog 3 (Drosophila); homer protein homolog 3; Homer, neuronal immediate early gene, 3; HOMER-3; VESL3

Molecular Weight

Mass (kDA):
39.836 kDA

Genomic Context


Human

Location:	19p13.11
Sequence:	19; NC_000019.10 (18929201..18941258, complement)

Subcellular Localizations

Cytoplasm. Cell junction, synapse, postsynaptic density. Cell junction, synapse. Postsynaptic density of neuronal cells.

Diseases

Urinary Incontinence
Leukemogenesis
Anxiety Disorders
Childhood Acute Myeloid Leukemia
Hematopoietic Neoplasms
Leukemia, Myelocytic, Acute
Patient Dependence On
Malignant Neoplasms
Myeloid Leukemia

Leukemia
Alzheimer's Disease
Senile Plaques
Stress, Psychological

Interacting Proteins

ABI2
ABI3
DYNLL2
EAF1
EFHC1

EIF3D
FAT1
HOMER1
LNX1
MOS

NEBL
PAX6
PKN1
POM121
PPP1R18

PRCC
PSMA1
SNRPF
USP2
WIPF1

Pathways

Cell Activation
Membrane Depolarization
Mrna Transcription
Regulation Of T Cell Activation
T Cell Activation
Localization

Secretion

PTMs

Phosphorylation

Dephosphorylation

Research Areas

Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HOMER3

References

PMID: 9808458 by Xiao B., et al. Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins.

PMID: 10653696 by Soloviev M., et al. Molecular characterisation of two structurally distinct groups of human homers, generated by extensive alternative splicing.