HMGN1 Antibodies

AND HMGN1 ELISA kits, HMGN1 Proteins

Many biological assays use antibodies to detect HMGN1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HMGN1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HMGN1 antibodies...

We validate the specificity of these antibodies to HMGN1 by testing them on tissues known to express HMGN1 positively and negatively. Browse below to find the HMGN1 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HMGN1 Infographic by Boster Bio

All HMGN1 Products

Product

Figures

Specificity

Applications

Price

Anti-IPO-38 HMGN1 Monoclonal Antibody

5 Q&As

Human

IHC, WB

$612
Cat # M03051
100ug

Anti-HMGN1 Antibody

Human, Mouse, Rat

$405
Cat # A03051
100ul

Anti-HMGN1 Antibody

Human, Mouse

IF, ICC, WB

$405
Cat # A03051-1
100ul

Anti-Phospho-HMG-14 (S21) HMGN1 Antibody

Human, Mouse, Rat

ELISA, IF, IHC

$380
Cat # A03051S21
100ul

Anti-HMG-14 HMGN1 Antibody

Human, Mouse, Rat

ELISA, IF, IHC

$380
Cat # A03051-2
100ul

HMG14 (HMGN1) (NM_004965) Human Recombinant Protein

$1249
Cat # PROTP05114
20 µg

HMG14 (HMGN1) (NM_004965) Human Over-expression Lysate

Human

$628
Cat # LS003150
100 µg

HMGN1 Overview

Facts about Non-histone chromosomal protein HMG-14.

HMGN1 3D structure. Source: alphafold

Non-histone chromosomal protein HMG-14 (HMGN1)

Binds to the interior side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation.

Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity). .

Gene Information

Human
Gene Name:	HMGN1
Uniprot:	P05114
Entrez:	3150

Family

Belongs to:

HMGN family

Alternative Names

FLJ31471; High mobility group nucleosome-binding domain-containing protein 1; high-mobility group (nonhistone chromosomal) protein 14; high-mobility group nucleosome binding 1; high-mobility group nucleosome binding domain 1; HMG14; HMG14FLJ27265; HMGN1; MGC104230; MGC117425; non-histone chromosomal protein HMG-14; nonhistone chromosomal protein HMG-14

Molecular Weight

Mass (kDA):
10.659 kDA

Genomic Context


Human

Location:	21q22.2
Sequence:	21; NC_000021.9 (39342315..39349088, complement)

Subcellular Localizations

Nucleus. Cytoplasm. Cytoplasmic enrichment upon phosphorylation. The RNA edited version localizes to the nucleus.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Breast
Genomic Instability
Neoplasms
Mammary Neoplasms
Cytogenetic Abnormality
Corneal Diseases
Down Syndrome
Cell Transformation, Neoplastic
Cockayne Syndrome
Neoplasm Metastasis
Amnesia

Neoplasms, Radiation-induced
Disorders Of Sex Development
Endometrial Polyp
Neoplasm Invasiveness
Carcinoma
Carcinoma In Situ
Innate Immune Response

Pathways

Chromatin Remodeling
Cell Cycle
Dna Repair
Transport
Atp-dependent Chromatin Remodeling
Immune Response
Hypersensitivity
Cell Cycle Arrest
Nuclear Import
Mitosis
Localization
Embryo Development
Metaphase

Protein Phosphorylation
Hair Follicle Development
Electron Transport
Electron Transport Chain
Sex Determination
Histone Phosphorylation
Nuclear Transport

PTMs

Phosphorylation
Acetylation

Deamination
Methylation

Dephosphorylation

Research Areas

Apoptosis
Breast Cancer
Cancer
Cell Cycle and Replication
Checkpoint signaling

Chromatin Research
Core ESC-Like Genes
DNA Double Strand Break Repair
DNA Repair
Epigenetics

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HMGN1

References

PMID: 3782107 by Landsman D., et al. Chromosomal protein HMG-14. Complete human cDNA sequence and evidence for a multigene family.

PMID: 2563381 by Landsman D., et al. Chromosomal protein HMG-14. Identification, characterization, and chromosome localization of a functional gene from the large human multigene family.